Literature DB >> 23293728

Case of obscure-overt gastrointestinal bleeding after pediatric liver transplantation explained by endoscopic ultrasound.

Gabriele Curcio1, Marta Di Pisa, Roberto Miraglia, Pieralba Catalano, Luca Barresi, Ilaria Tarantino, Antonino Granata, Marco Spada, Mario Traina.   

Abstract

Portal hypertension, which is a common finding in children awaiting liver transplantation, is also found after transplantation. It's reported the case of a 6-year-old girl, transplanted for biliary atresia, who had a severe obscure-overt bleeding presenting with melena. An esophagogastroduodenoscopy showed several duodenal small, bulging lesions, with some red signs. Near the lesions, a depressed area of 2 cm, covered with mixed hyperemic and white mucosa, was observed. To better evaluate these lesions, we performed an endoscopic ultrasonography (EUS) that showed multiple, round hypoechoic areas 0.5-5 mm in diameter, compatible with duodenal varices, and several periduodenal anechoic lesions compatible with collaterals. A consecutive computed tomography scan showed a stenosis of the portal vein anastomosis confirmed with a transhepatic portography, which was successfully treated with balloon angioplasty. No further episodes of bleeding were observed during the follow-up. This case report suggests that EUS is safe and feasible in young children when using echoendoscopes designed for use in adults. However further studies are needed to validate the employment of this technique in the management and follow-up of pediatric portal hypertension.

Entities:  

Keywords:  Endoscopic ultrasound; Gastrointestinal; Liver transplantation; Obscure bleeding; Pediatric

Year:  2012        PMID: 23293728      PMCID: PMC3536855          DOI: 10.4253/wjge.v4.i12.571

Source DB:  PubMed          Journal:  World J Gastrointest Endosc


  13 in total

Review 1.  Vascular complications after orthotopic liver transplantation: hepatic artery thrombosis.

Authors:  E Pareja; M Cortes; R Navarro; F Sanjuan; R López; J Mir
Journal:  Transplant Proc       Date:  2010-10       Impact factor: 1.066

Review 2.  Management of ectopic varices.

Authors:  I D Norton; J C Andrews; P S Kamath
Journal:  Hepatology       Date:  1998-10       Impact factor: 17.425

3.  Impact of EUS in the evaluation of pancreaticobiliary disorders in children.

Authors:  Shyam Varadarajulu; C Mel Wilcox; Mohamad A Eloubeidi
Journal:  Gastrointest Endosc       Date:  2005-08       Impact factor: 9.427

4.  Roux-en-Y loop varices in children with portal hypertension after liver transplantation: an unusual cause of "obscure" gastrointestinal bleeding.

Authors:  Jaime Chu; Nanda Kerkar; Tamir A Miloh; Gonzalo Rodriguez-Laiz; Blair Lewis; Anondo Stangl; Kimberly P Newton; Kishore Iyer; Ronen Arnon
Journal:  Pediatr Transplant       Date:  2010-07-01

5.  Biliary complications in pediatric living related liver transplantation.

Authors:  H Egawa; S Uemoto; Y Inomata; A M Shapiro; K Asonuma; T Kiuchi; H Okajima; K Itou; K Tanaka
Journal:  Surgery       Date:  1998-11       Impact factor: 3.982

6.  Diagnosis and interventional radiological treatment of vascular and biliary complications after liver transplantation in children with biliary atresia.

Authors:  H-L Chen; A M Concejero; T-L Huang; T-Y Chen; L L-C Tsang; C-C Wang; S-H Wang; C-L Chen; Yu-Fan Cheng
Journal:  Transplant Proc       Date:  2008-10       Impact factor: 1.066

Review 7.  Endoscopic ultrasonography (EUS) in portal hypertension.

Authors:  P Bocus; M Ceolin; G Battaglia
Journal:  Minerva Med       Date:  2007-08       Impact factor: 4.806

8.  Endoscopic ultrasonography in pediatric patients with gastrointestinal disorders.

Authors:  Shlomi Cohen; Michael Kalinin; Ayala Yaron; Shlomo Givony; Shimon Reif; Erwin Santo
Journal:  J Pediatr Gastroenterol Nutr       Date:  2008-05       Impact factor: 2.839

9.  Living related liver transplantation for an infant with biliary atresia.

Authors:  Shu-Sen Zheng; Dong-Sheng Huang; Wei-Lin Wang; Ting-Bo Liang; Min Zhang; Yan Shen; An-Wei Lu; Sheng-Yang Liao; Xiao Xu
Journal:  Hepatobiliary Pancreat Dis Int       Date:  2002-05

10.  Management of portal hypertension in children.

Authors:  Elizabeth Mileti; Philip Rosenthal
Journal:  Curr Gastroenterol Rep       Date:  2011-02
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  1 in total

Review 1.  The role of EUS in diagnosis and treatment of liver disorders.

Authors:  Sara Campos; Jan-Werner Poley; Lydi van Driel; Marco J Bruno
Journal:  Endosc Int Open       Date:  2019-10-01
  1 in total

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