Literature DB >> 23292310

Clinical activity of sunitinib in patients with advanced desmoplastic round cell tumor: a case series.

Antoine Italiano1, Michèle Kind2, Angela Cioffi3, Robert G Maki4,5, Binh Bui6.   

Abstract

Desmoplastic small round cell tumor (DSRCT) is a rare and aggressive malignancy with poor outcome occurring in adolescents and young adults. Therapeutic options for patients with advanced disease are limited. Preclinical studies have shown that VEGFR-2 and VEGFA are overexpressed in DSRCT and that DSRCT xenografts were highly responsive to anti-VEGF agents such as bevacizumab. We report here the clinical activity of sunitinib in eight patients with DSCRT. Our data suggest that sunitinib may be associated with clinical benefit even in heavily pretreated patients.

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Year:  2013        PMID： 23292310     DOI： 10.1007/s11523-012-0251-8

Source DB:  PubMed          Journal:  Target Oncol        ISSN： 1776-2596            Impact factor:   4.493


  4 in total

Review 1.  The diagnosis and management of desmoplastic small round cell tumor: a review.

Authors:  Andrea Hayes-Jordan; Peter M Anderson
Journal:  Curr Opin Oncol       Date:  2011-07       Impact factor: 3.645

2.  Intra-abdominal desmoplastic small round cell tumor: immunohistochemical evidence for up-regulation of autocrine and paracrine growth factors.

Authors:  K Froberg; R E Brown; H Gaylord; C Manivel
Journal:  Ann Clin Lab Sci       Date:  1999 Jan-Mar       Impact factor: 1.256

Review 3.  Sunitinib: from rational design to clinical efficacy.

Authors:  Laura Q M Chow; S Gail Eckhardt
Journal:  J Clin Oncol       Date:  2007-03-01       Impact factor: 44.544

4.  Multicenter phase II trial of sunitinib in the treatment of nongastrointestinal stromal tumor sarcomas.

Authors:  Suzanne George; Priscilla Merriam; Robert G Maki; Annick D Van den Abbeele; Jeffrey T Yap; Timothy Akhurst; David C Harmon; Gauri Bhuchar; Margaret M O'Mara; David R D'Adamo; Jeffrey Morgan; Gary K Schwartz; Andrew J Wagner; James E Butrynski; George D Demetri; Mary L Keohan
Journal:  J Clin Oncol       Date:  2009-05-18       Impact factor: 44.544
  4 in total
  16 in total

1.  Requirement for novel surgical and clinical protocols for the treatment of desmoplastic small round cell tumor: A report of two cases and a review of the literature.

Authors:  Diego Cezar DA Silva Pechutti; Pedro Luiz DE Arruda Lourençao; Bonifacio Katsunori Takegawa; Cristiano Claudino Oliveira; Alexandre Neto
Journal:  Oncol Lett       Date:  2015-05-27       Impact factor: 2.967

2.  Multimodality Treatment of Desmoplastic Small Round Cell Tumor: Chemotherapy and Complete Cytoreductive Surgery Improve Patient Survival.

Authors:  Vivek Subbiah; Salah-Eddine Lamhamedi-Cherradi; Branko Cuglievan; Brian A Menegaz; Pamela Camacho; Winston Huh; Vandhana Ramamoorthy; Pete M Anderson; Raphael E Pollock; Dina C Lev; Wei Qiao; Mary Frances McAleer; Robert S Benjamin; Shreyaskumar Patel; Cynthia E Herzog; Najat C Daw; Barry W Feig; Alexander J Lazar; Andrea Hayes-Jordan; Joseph A Ludwig
Journal:  Clin Cancer Res       Date:  2018-06-05       Impact factor: 12.531

Review 3.  Advances in the Management of Pediatric Sarcomas.

Authors:  Fiorela N Hernandez Tejada; Alejandro Zamudio; Mario L Marques-Piubelli; Branko Cuglievan; Douglas Harrison
Journal:  Curr Oncol Rep       Date:  2020-11-16       Impact factor: 5.075

4.  Myeloablative chemotherapy with autologous stem cell transplant for desmoplastic small round cell tumor.

Authors:  Christopher J Forlenza; Brian H Kushner; Nancy Kernan; Farid Boulad; Heather Magnan; Leonard Wexler; Suzanne L Wolden; Michael P LaQuaglia; Shakeel Modak
Journal:  Sarcoma       Date:  2015-04-07

5.  Antiangiogenic effects in patients with progressive desmoplastic small round cell tumor: data from the French national registry dedicated to the use of off-labeled targeted therapy in sarcoma (OUTC's).

Authors:  Sarah Bétrian; Christophe Bergeron; Jean-Yves Blay; Emmanuelle Bompas; Philippe A Cassier; Laure Chevallier; Jérome Fayette; Magali Girodet; Cécile Guillemet; Axel Le Cesne; Perrine Marec-Berard; Isabelle Ray-Coquard; Christine Chevreau
Journal:  Clin Sarcoma Res       Date:  2017-05-10

6.  Abdominal desmoplastic small round cell tumor without extraperitoneal metastases: Is there a benefit for HIPEC after macroscopically complete cytoreductive surgery?

Authors:  C Honoré; V Atallah; O Mir; D Orbach; G Ferron; C LePéchoux; J B Delhorme; P Philippe-Chomette; S Sarnacki; S Msika; P Terrier; O Glehen; H Martelli; V Minard-Colin; F Bertucci; J Y Blay; S Bonvalot; D Elias; A LeCesne; P Sargos
Journal:  PLoS One       Date:  2017-02-24       Impact factor: 3.240

7.  Pazopanib in advanced desmoplastic small round cell tumours: a multi-institutional experience.

Authors:  Anna Maria Frezza; Charlotte Benson; Ian R Judson; Saskia Litiere; Sandrine Marreaud; Stefan Sleijfer; Jean-Yves Blay; Raz Dewji; Cyril Fisher; Winette van der Graaf; Larry Hayward
Journal:  Clin Sarcoma Res       Date:  2014-07-29

8.  Desmoplastic small round cell tumour: characteristics and prognostic factors of 41 patients and review of the literature.

Authors:  Han Hsi Wong; Helen M Hatcher; Charlotte Benson; Omar Al-Muderis; Gail Horan; Cyril Fisher; Helena M Earl; Ian Judson
Journal:  Clin Sarcoma Res       Date:  2013-11-26

Review 9.  Effective treatment of apatinib in desmoplastic small round cell tumor: a case report and literature review.

Authors:  Chunyu Shi; Ye Feng; Lei Chao Zhang; Da Yong Ding; Ming Yu Yan; Lu Pan
Journal:  BMC Cancer       Date:  2018-03-27       Impact factor: 4.430

10.  Clinical Activity of Pazopanib in Patients with Advanced Desmoplastic Small Round Cell Tumor.

Authors:  Brian A Menegaz; Branko Cuglievan; Jalen Benson; Pamela Camacho; Salah-Eddine Lamhamedi-Cherradi; Cheuk Hong Leung; Carla L Warneke; Winston Huh; Vivek Subbiah; Robert S Benjamin; Shreyaskumar Patel; Najat Daw; Andrea Hayes-Jordan; Joseph A Ludwig
Journal:  Oncologist       Date:  2017-12-06
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