L Radzevičienė1, R Ostrauskas. 1. Institute of Endocrinology, Medical Academy, Lithuanian University of Health Sciences, Eiveniu 2, 50009 Kaunas, Lithuania. lina_radzeviciene@yahoo.com
Abstract
OBJECTIVE: To assess the relationship between various anthropometric indexes and risk for type 2 diabetes in women. STUDY DESIGN AND METHODS: A case-control study of 168 cases with newly diagnosed type 2 diabetes and 336 controls who were free of the disease. Cases and controls (ratio 1:2) were matched by age (±5 years). A questionnaire was used to collect information on possible risk factors for type 2 diabetes. Odds ratios (OR) and 95% confidence intervals (CI) for type 2 diabetes were calculated by conditional logistic regression. RESULTS: After adjustment for possible confounders, increased risk for type 2 diabetes was associated with body mass index (BMI) ≥30 kg/m(2) (OR 4.68, 95% CI 2.09-10.49), waist circumference (WC) >88 cm (OR 6.99, 95% CI 1.60-30.42) and waist-height ratio (WHtR) ≥0.5 (OR 3.15, 95% CI 1.91-15.81). CONCLUSIONS: Both general and central obesity are associated with type 2 diabetes. The results suggest that high BMI, WC and WHtR are significant risk factors for type 2 diabetes in women. Crown
OBJECTIVE: To assess the relationship between various anthropometric indexes and risk for type 2 diabetes in women. STUDY DESIGN AND METHODS: A case-control study of 168 cases with newly diagnosed type 2 diabetes and 336 controls who were free of the disease. Cases and controls (ratio 1:2) were matched by age (±5 years). A questionnaire was used to collect information on possible risk factors for type 2 diabetes. Odds ratios (OR) and 95% confidence intervals (CI) for type 2 diabetes were calculated by conditional logistic regression. RESULTS: After adjustment for possible confounders, increased risk for type 2 diabetes was associated with body mass index (BMI) ≥30 kg/m(2) (OR 4.68, 95% CI 2.09-10.49), waist circumference (WC) >88 cm (OR 6.99, 95% CI 1.60-30.42) and waist-height ratio (WHtR) ≥0.5 (OR 3.15, 95% CI 1.91-15.81). CONCLUSIONS: Both general and central obesity are associated with type 2 diabetes. The results suggest that high BMI, WC and WHtR are significant risk factors for type 2 diabetes in women. Crown
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