Literature DB >> 23288360

A popular engagement at the ends.

Neal F Lue1, Eun Young Yu, Ming Lei.   

Abstract

Three recent studies converged on a specific protein-protein interface between TPP1 and telomerase as being crucial for the regulation of both telomerase recruitment and processivity in mammalian cells. An equivalent interaction appears to exist in budding yeast, making this a nearly universal means of telomerase regulation.

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Year:  2013        PMID： 23288360      PMCID： PMC5560596          DOI： 10.1038/nsmb.2483

Source DB:  PubMed          Journal:  Nat Struct Mol Biol        ISSN： 1545-9985            Impact factor:   15.369


  27 in total

1.  Human telomerase domain interactions capture DNA for TEN domain-dependent processive elongation.

Authors:  Aaron R Robart; Kathleen Collins
Journal:  Mol Cell       Date:  2011-04-21       Impact factor: 17.970

Review 2.  Role of telomeres and telomerase in cancer.

Authors:  Jerry W Shay; Woodring E Wright
Journal:  Semin Cancer Biol       Date:  2011-10-17       Impact factor: 15.707

3.  Mutual dependence of Candida albicans Est1p and Est3p in telomerase assembly and activation.

Authors:  Min Hsu; Eun Young Yu; Sunitha M Singh; Neal F Lue
Journal:  Eukaryot Cell       Date:  2007-06-01

4.  The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.

Authors:  Jayakrishnan Nandakumar; Caitlin F Bell; Ina Weidenfeld; Arthur J Zaug; Leslie A Leinwand; Thomas R Cech
Journal:  Nature       Date:  2012-10-24       Impact factor: 69.504

5.  The POT1-TPP1 telomere complex is a telomerase processivity factor.

Authors:  Feng Wang; Elaine R Podell; Arthur J Zaug; Yuting Yang; Paul Baciu; Thomas R Cech; Ming Lei
Journal:  Nature       Date:  2007-01-21       Impact factor: 69.504

6.  Tel1ATM and Rad3ATR kinases promote Ccq1-Est1 interaction to maintain telomeres in fission yeast.

Authors:  Bettina A Moser; Ya-Ting Chang; Jorgena Kosti; Toru M Nakamura
Journal:  Nat Struct Mol Biol       Date:  2011-11-20       Impact factor: 15.369

7.  The Pot1a-associated proteins Tpt1 and Pat1 coordinate telomere protection and length regulation in Tetrahymena.

Authors:  Benjamin R Linger; Gregg B Morin; Carolyn M Price
Journal:  Mol Biol Cell       Date:  2011-09-07       Impact factor: 4.138

8.  Specificity requirements for human telomere protein interaction with telomerase holoenzyme.

Authors:  Alec N Sexton; Daniel T Youmans; Kathleen Collins
Journal:  J Biol Chem       Date:  2012-08-14       Impact factor: 5.486

9.  (PS)2: protein structure prediction server.

Authors:  Chih-Chieh Chen; Jenn-Kang Hwang; Jinn-Moon Yang
Journal:  Nucleic Acids Res       Date:  2006-07-01       Impact factor: 16.971

10.  A proposed OB-fold with a protein-interaction surface in Candida albicans telomerase protein Est3.

Authors:  Eun Young Yu; Feng Wang; Ming Lei; Neal F Lue
Journal:  Nat Struct Mol Biol       Date:  2008-09       Impact factor: 18.361
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  7 in total

1.  Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions.

Authors:  Jiansen Jiang; Henry Chan; Darian D Cash; Edward J Miracco; Rachel R Ogorzalek Loo; Heather E Upton; Duilio Cascio; Reid O'Brien Johnson; Kathleen Collins; Joseph A Loo; Z Hong Zhou; Juli Feigon
Journal:  Science       Date:  2015-10-15       Impact factor: 47.728

2.  Defective repair of uracil causes telomere defects in mouse hematopoietic cells.

Authors:  Haritha Vallabhaneni; Fang Zhou; Robert W Maul; Jaya Sarkar; Jinhu Yin; Ming Lei; Lea Harrington; Patricia J Gearhart; Yie Liu
Journal:  J Biol Chem       Date:  2015-01-08       Impact factor: 5.157

3.  Telomerase enzymatic component hTERT shortens long telomeres in human cells.

Authors:  Yun-Ling Zheng; Fan Zhang; Bing Sun; Juan Du; Chongkui Sun; Jie Yuan; Ying Wang; Lian Tao; Krishna Kota; Xuefeng Liu; Richard Schlegel; Qin Yang
Journal:  Cell Cycle       Date:  2014-04-10       Impact factor: 5.173

4.  Structure of Est3 reveals a bimodal surface with differential roles in telomere replication.

Authors:  Timsi Rao; Johnathan W Lubin; Geoffrey S Armstrong; Timothy M Tucey; Victoria Lundblad; Deborah S Wuttke
Journal:  Proc Natl Acad Sci U S A       Date:  2013-12-16       Impact factor: 12.779

5.  Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation.

Authors:  Alec N Sexton; Samuel G Regalado; Christine S Lai; Gregory J Cost; Colleen M O'Neil; Fyodor D Urnov; Philip D Gregory; Rudolf Jaenisch; Kathleen Collins; Dirk Hockemeyer
Journal:  Genes Dev       Date:  2014-08-15       Impact factor: 12.890

6.  Systematic analysis of human telomeric dysfunction using inducible telosome/shelterin CRISPR/Cas9 knockout cells.

Authors:  Hyeung Kim; Feng Li; Quanyuan He; Tingting Deng; Jun Xu; Feng Jin; Cristian Coarfa; Nagireddy Putluri; Dan Liu; Zhou Songyang
Journal:  Cell Discov       Date:  2017-09-26       Impact factor: 10.849

7.  Single-molecule imaging of telomerase reverse transcriptase in human telomerase holoenzyme and minimal RNP complexes.

Authors:  Robert Alexander Wu; Yavuz S Dagdas; S Tunc Yilmaz; Ahmet Yildiz; Kathleen Collins
Journal:  Elife       Date:  2015-10-12       Impact factor: 8.140
  7 in total

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