Literature DB >> 23288315

[Accidental staining of corneal nerves by methylene blue].

S Peter1, E Reichart, L Poyntner, S Mennel.   

Abstract

A 10-year-old child presented after accidental exposure of the left eye to a blue hair dye containing methylene blue. Mild ocular surface changes and a selective blue staining of the usually invisible corneal nerve fibre bundles were present. Corneal sensitivity was reduced. Despite copious lubrication a transient neurotrophic keratitis developed which did not resolve until corneal sensitivity became normal 2 weeks later. Association of mild chemical burns with neurotrophic keratitis is unusual but is of high clinical relevance as keratitis is a vision-threatening complication.

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Year:  2013        PMID: 23288315     DOI: 10.1007/s00347-012-2747-0

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN: 0941-293X            Impact factor:   1.059


  7 in total

Review 1.  Corneal nerves: structure, contents and function.

Authors:  Linda J Müller; Carl F Marfurt; Friedrich Kruse; Timo M T Tervo
Journal:  Exp Eye Res       Date:  2003-05       Impact factor: 3.467

2.  [Chemical and thermal eye burns. Conservatíve and surgical options of a stage-dependent therapy].

Authors:  H G Struck; N F Schrage
Journal:  Ophthalmologe       Date:  2011-10       Impact factor: 1.059

3.  Severe toxic effect of methylene blue 1% on iris epithelium and corneal endothelium.

Authors:  Dimitrios Brouzas; Dimitrios Droutsas; Antonios Charakidas; Ioannis Malias; Efstratia Georgiadou; Michael Apostolopoulos; Michael Moschos
Journal:  Cornea       Date:  2006-05       Impact factor: 2.651

4.  A critical evaluation of methods used to demonstrate tissue neural elements, illustrated by reference to the cornea.

Authors:  G WEDDELL; E ZANDER
Journal:  J Anat       Date:  1950-04       Impact factor: 2.610

5.  Comparison of dyes for cataract surgery. Part 1: cytotoxicity to corneal endothelial cells in a rabbit model.

Authors:  Yi-Sheng Chang; Shih-Ya Tseng; Sung-Huei Tseng; Ying-Ting Chen; Jing-Hsing Hsiao
Journal:  J Cataract Refract Surg       Date:  2005-04       Impact factor: 3.351

Review 6.  Cellular and molecular actions of Methylene Blue in the nervous system.

Authors:  Murat Oz; Dietrich E Lorke; Mohammed Hasan; George A Petroianu
Journal:  Med Res Rev       Date:  2011-01       Impact factor: 12.944

7.  The use of dye in ophthalmology.

Authors:  J K Singh; F E Dhawahir; A F A Hamid; P B Chell
Journal:  J Audiov Media Med       Date:  2004-06
  7 in total

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