Literature DB >> 23288135

Photodynamic therapy for retinal capillary hemangioma.

V P Papastefanou1, S Pilli, A Stinghe, A J Lotery, V M L Cohen.   

Abstract

PURPOSE: To describe the results of photodynamic therapy (PDT) for juxtapapillary and peripheral retinal capillary hemangioma (RCH). PATIENTS AND METHODS: Interventional case series of four eyes (four patients) with juxtapapillary RCH and one eye (one patient) with peripheral RCH. Two eyes with juxtapapillary RCH had received two sessions of full-fluence, double-duration PDT; whereas other two eyes had received single session of half-fluence, single-duration PDT. The peripheral RCH was treated with a single session of full-fluence, single-duration PDT.
RESULTS: Two patients had von Hippel-Lindau disease. Follow-up duration ranged from 4 months to 1 year. Pre-PDT visual acuity (VA) ranged from 20/200 to HM (juxtapapillary RCH) and 20/100 (peripheral RCH). Among the eyes with juxtapapillary RCH, tumor regression with partial resolution of macular edema was noted in two eyes (one eye each with half-fluence and full-fluence PDT), whereas two eyes had no change in tumor size with persistent macular edema. VA remained stable in three eyes and declined in one eye. In an eye with peripheral RCH, regression of tumor and macular edema with VA improvement was noted. Post-PDT complications included epiretinal membrane (one eye) and transient exudative retinal detachment (one eye).
CONCLUSION: PDT can be effective in reducing macular edema associated with RCH but this does not always correspond with an improvement in VA especially for juxtapapillary tumors.

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Year:  2013        PMID: 23288135      PMCID: PMC3597867          DOI: 10.1038/eye.2012.259

Source DB:  PubMed          Journal:  Eye (Lond)        ISSN: 0950-222X            Impact factor:   3.775


  12 in total

1.  Exudative retinal detachment following photodynamic therapy for retinal capillary hemangioma.

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2.  Transient serous retinal detachment in classic and occult choroidal neovascularization after photodynamic therapy.

Authors:  Stefan Mennel; Carsten H Meyer; Fred Eggarter; Silvia Peter
Journal:  Am J Ophthalmol       Date:  2005-10       Impact factor: 5.258

3.  Photodynamic (verteporfin) therapy for retinal capillary haemangioma, with monitoring of feeder and draining blood vessel diameters.

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Journal:  Acta Ophthalmol Scand       Date:  2005-08

4.  Combined treatment of a juxtapapillary retinal capillary haemangioma with intravitreal bevacizumab and photodynamic therapy.

Authors:  F Ziemssen; M Voelker; W Inhoffen; K U Bartz-Schmidt; F Gelisken
Journal:  Eye (Lond)       Date:  2007-06-01       Impact factor: 3.775

5.  Photodynamic therapy in the management of juxtapapillary capillary haemangiomas.

Authors:  Jonathan R Golshevsky; Justin O'Day
Journal:  Clin Exp Ophthalmol       Date:  2005-10       Impact factor: 4.207

6.  Three cases of large retinal capillary hemangiomas treated with verteporfin and photodynamic therapy.

Authors:  Thomas M Aaberg; Thomas M Aaberg; Daniel F Martin; James P Gilman; Robert Myles
Journal:  Arch Ophthalmol       Date:  2005-03

7.  Verteporfin photodynamic therapy of six eyes with retinal capillary haemangioma.

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8.  Combined intravitreal anti-vascular endothelial growth factor (Avastin) and photodynamic therapy to treat retinal juxtapapillary capillary haemangioma.

Authors:  Stefan Mennel; Carsten H Meyer; Josep Callizo
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9.  Treatment of retinal capillary hemangioma.

Authors:  Arun D Singh; Mahnaz Nouri; Carol L Shields; Jerry A Shields; Noel Perez
Journal:  Ophthalmology       Date:  2002-10       Impact factor: 12.079

10.  Subretinal hemorrhage after photodynamic therapy for juxtapapillary retinal capillary hemangioma.

Authors:  Takayuki Baba; Masayasu Kitahashi; Mariko Kubota-Taniai; Toshiyuki Oshitari; Shuichi Yamamoto
Journal:  Case Rep Ophthalmol       Date:  2011-04-22
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  13 in total

1.  [Differential diagnosis of papilledema and macular exudation-the exophytically growing juxtapapillary retinal capillary hemangioma].

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2.  Superficial hemangioma is better treated by topical 5-aminolevulinic followed by 595-nm pulsed dye laser therapy rather than 595-nm laser therapy alone.

Authors:  Ming Zeng; Songke Shen; Wei Chen; Chunjun Yang; ShengXiu Liu
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Review 3.  MANAGEMENT OF RETINAL HEMANGIOBLASTOMA IN VON HIPPEL-LINDAU DISEASE.

Authors:  Henry E Wiley; Valerie Krivosic; Alain Gaudric; Michael B Gorin; Carol Shields; Jerry Shields; Mary E Aronow; Emily Y Chew
Journal:  Retina       Date:  2019-12       Impact factor: 4.256

4.  Photodynamic therapy for juxtapapillary retinal capillary hemangioma.

Authors:  Panagiotis G Mitropoulos; Irini P Chatziralli; Vasileios G Peponis; Vasileia A Tsiotra; Efstratios A Parikakis
Journal:  Case Rep Ophthalmol Med       Date:  2014-03-03

5.  25-gauge vitrectomy combined with half-fluence photodynamic therapy for the treatment of juxtapapillary retinal capillary hemangioma: a case report.

Authors:  Cesare Mariotti; Alfonso Giovannini; Michele Reibaldi; Michele Nicolai; Andrea Saitta
Journal:  Case Rep Ophthalmol       Date:  2014-05-29

6.  Massive exudative retinal detachment following photodynamic therapy and intravitreal bevacizumab injection in retinal capillary hemangioma.

Authors:  Hyeong Min Kim; Kyu Hyung Park; Se Joon Woo
Journal:  Korean J Ophthalmol       Date:  2015-04

Review 7.  Juxtapapillary retinal capillary hemangioma: new therapeutic strategies.

Authors:  Andrea Saitta; Michele Nicolai; Alfonso Giovannini; Cesare Mariotti
Journal:  Med Hypothesis Discov Innov Ophthalmol       Date:  2014

8.  Repurposing propranolol as a drug for the treatment of retinal haemangioblastomas in von Hippel-Lindau disease.

Authors:  Virginia Albiñana; Rosa María Jiménez Escribano; Isabel Soler; Luis Rodríguez Padial; Lucia Recio-Poveda; Karina Villar Gómez de Las Heras; Luisa María Botella
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9.  Effect of intravitreal dexamethasone on macular edema in von Hippel-Lindau disease assessed using swept-source optical coherence tomography: a case report.

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Journal:  J Med Case Rep       Date:  2018-09-06

10.  The follow-up observation on the therapeutic effect of photodynamic therapy for the juxtapapillary retinal capillary hemangioma: a case report.

Authors:  Bainan Tong; Jun Xiao; Guanfang Su
Journal:  BMC Ophthalmol       Date:  2018-10-26       Impact factor: 2.209

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