Literature DB >> 2328795

[The characteristics of the temporal dynamics of stereotypic behavior in rats during chronic fenamine administration].

E B Arushanian, A V Popov.   

Abstract

Amphetamine-induced stereotyped behavior is a nonsteady oscillatory process. In its structure waves with 2-3, 4-5 and 10-15 minute periods may be distinguished. In some animals (30%) after chronic amphetamine administration the stereotyped behavior was attenuated with reorganization of its rhythmical pattern but in other cases (35%) stereotype on the contrary increased. Tolerance developed in the animals which had initially the more pronounced stereotype with the predomination of short-period (2-3 min) waves on the chronogram. These animals demonstrated low locomotor activity in the opened field, greater immobility in the forced swimming test and better relearning in Y-maze.

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Year:  1990        PMID: 2328795

Source DB:  PubMed          Journal:  Farmakol Toksikol        ISSN: 0014-8318


  1 in total

1.  Influence of damage to the suprachiasmatic nuclei of the hypothalamus of rats on the dynamics of short-period fluctuations of normal and abnormal behavior.

Authors:  E B Arushanyan; A V Popov
Journal:  Neurosci Behav Physiol       Date:  1995 Jul-Aug
  1 in total

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