Literature DB >> 23287884

DNA nanostructure serum stability: greater than the sum of its parts.

Justin W Conway1, Christopher K McLaughlin, Katherine J Castor, Hanadi Sleiman.   

Abstract

Simple chemical modifications to oligonucleotide ends with hexaethylene glycol and hexanediol are shown to significantly increase nuclease resistance under serum conditions. The modified oligonucleotides were used to construct DNA prismatic cages in a single step and in quantitative yield. These cages further stabilize their strands towards nucleases, with lifetimes of 62 hours in serum. The cages contain a large number of single-stranded regions for functionalization, illustrating their versatility for biological applications.

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Year:  2013        PMID： 23287884     DOI： 10.1039/c2cc37556g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  37 in total

Review 1.  DNA nanotechnology from the test tube to the cell.

Authors:  Yuan-Jyue Chen; Benjamin Groves; Richard A Muscat; Georg Seelig
Journal:  Nat Nanotechnol       Date:  2015-09       Impact factor: 39.213

2.  DNA nanostructures: a shift from assembly to applications.

Authors:  Laura A Lanier; Harry Bermudez
Journal:  Curr Opin Chem Eng       Date:  2015-02-01       Impact factor: 5.163

3.  Sensitization of transforming growth factor-β signaling by multiple peptides patterned on DNA nanostructures.

Authors:  Ronnie O Pedersen; Elizabeth G Loboa; Thomas H LaBean
Journal:  Biomacromolecules       Date:  2013-11-08       Impact factor: 6.988

4.  Facile Assembly/Disassembly of DNA Nanostructures Anchored on Cell-Mimicking Giant Vesicles.

Authors:  Ruizi Peng; Huijing Wang; Yifan Lyu; Liujun Xu; Hui Liu; Hailan Kuai; Qiaoling Liu; Weihong Tan
Journal:  J Am Chem Soc       Date:  2017-08-30       Impact factor: 15.419

5.  Hybrid DNA/RNA nanostructures with 2'-5' linkages.

Authors:  Arun Richard Chandrasekaran; Johnsi Mathivanan; Parisa Ebrahimi; Javier Vilcapoma; Alan A Chen; Ken Halvorsen; Jia Sheng
Journal:  Nanoscale       Date:  2020-11-05       Impact factor: 7.790

Review 6.  Nanoscale delivery systems for microRNAs in cancer therapy.

Authors:  Sanda Boca; Diana Gulei; Alina-Andreea Zimta; Anca Onaciu; Lorand Magdo; Adrian Bogdan Tigu; Calin Ionescu; Alexandru Irimie; Rares Buiga; Ioana Berindan-Neagoe
Journal:  Cell Mol Life Sci       Date:  2019-10-21       Impact factor: 9.261

7.  Effect of 2'-5'/3'-5' phosphodiester linkage heterogeneity on RNA interference.

Authors:  Maryam Habibian; S Harikrishna; Johans Fakhoury; Maria Barton; Eman A Ageely; Regina Cencic; Hassan H Fakih; Adam Katolik; Mayumi Takahashi; John Rossi; Jerry Pelletier; Keith T Gagnon; P I Pradeepkumar; Masad J Damha
Journal:  Nucleic Acids Res       Date:  2020-05-21       Impact factor: 16.971

Review 8.  DNA nanomaterials for preclinical imaging and drug delivery.

Authors:  Dawei Jiang; Christopher G England; Weibo Cai
Journal:  J Control Release       Date:  2016-08-13       Impact factor: 9.776

9.  Nuclease Degradation Analysis of DNA Nanostructures Using Gel Electrophoresis.

Authors:  Arun Richard Chandrasekaran; Ken Halvorsen
Journal:  Curr Protoc Nucleic Acid Chem       Date:  2020-09

10.  Kinetics of heterochiral strand displacement from PNA-DNA heteroduplexes.

Authors:  Nandini Kundu; Brian E Young; Jonathan T Sczepanski
Journal:  Nucleic Acids Res       Date:  2021-06-21       Impact factor: 16.971
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