Sleep loss and risk-taking behavior: a review of the literature.

Sleep loss is common problem with a wide range of consequences. One possible consequence of sleep loss may be risk-taking behavior (RTB). The present review examined the empirical literature on the relationship between sleep loss and RTB. We found 23 studies that met inclusion criteria. Overall, sleep loss was positively associated with RTB, and there was evidence that changes in sleep loss are causally related to changes in RTB. One possible mediator of the relationship between sleep loss and RTB was reduced functioning of the ventromedial prefrontal cortex (VMPFC). Possible moderators of this relationship included type of RTB measure and general versus specific RTB. We discussed limitations and recommendations for future research in this area.