Literature DB >> 23286384

Observations on the modified Wenker synthesis of aziridines and the development of a biphasic system.

Benjamin R Buckley1, Anish P Patel, K G U Wijayantha.   

Abstract

A cheap and reliable process for the modified Wenker cyclization to afford aziridines has been achieved using biphasic conditions for a range of amino alcohol starting materials. A 100 mmol "one-pot" process has also been devised, and the enantiopurity of the starting amino alcohol is retained in the aziridine product.

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Year:  2013        PMID： 23286384     DOI： 10.1021/jo302615g

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

Review 1.  Transition metal-free one-pot synthesis of nitrogen-containing heterocycles.

Authors:  Simpal Kumari; Dharma Kishore; Sarvesh Paliwal; Rajani Chauhan; Jaya Dwivedi; Aakanksha Mishra
Journal:  Mol Divers       Date:  2015-06-09       Impact factor: 2.943

2.  Crystal structure of [2-(tri-ethyl-ammonio)-eth-yl][(2,4,6-triiso-propyl-phen-yl)sulfon-yl]amide tetra-hydrate.

Authors:  C Golz; C Strohmann
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2015-04-30

3.  Copper-Catalyzed Ring-Opening Reactions of Alkyl Aziridines with B2pin2: Experimental and Computational Studies.

Authors:  Lucilla Favero; Andrea Menichetti; Cosimo Boldrini; Lucrezia Margherita Comparini; Valeria Di Bussolo; Sebastiano Di Pietro; Mauro Pineschi
Journal:  Molecules       Date:  2021-12-06       Impact factor: 4.411
  3 in total

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