BACKGROUND: Depression after stroke is a distressing problem that may be associated with other negative health outcomes. AIMS: To estimate the natural history, predictors and outcomes of depression after stroke. METHOD: Studies published up to 31 August 2011 were searched and reviewed according to accepted criteria. RESULTS: Out of 13 558 references initially found, 50 studies were included. Prevalence of depression was 29% (95% CI 25-32), and remains stable up to 10 years after stroke, with a cumulative incidence of 39-52% within 5 years of stroke. The rate of recovery from depression among patients depressed a few months after stroke ranged from 15 to 57% 1 year after stroke. Major predictors of depression are disability, depression pre-stroke, cognitive impairment, stroke severity and anxiety. Lower quality of life, mortality and disability are independent outcomes of depression after stroke. CONCLUSION: Interventions for depression and its potential outcomes are required.
BACKGROUND: Depression after stroke is a distressing problem that may be associated with other negative health outcomes. AIMS: To estimate the natural history, predictors and outcomes of depression after stroke. METHOD: Studies published up to 31 August 2011 were searched and reviewed according to accepted criteria. RESULTS: Out of 13 558 references initially found, 50 studies were included. Prevalence of depression was 29% (95% CI 25-32), and remains stable up to 10 years after stroke, with a cumulative incidence of 39-52% within 5 years of stroke. The rate of recovery from depression among patients depressed a few months after stroke ranged from 15 to 57% 1 year after stroke. Major predictors of depression are disability, depression pre-stroke, cognitive impairment, stroke severity and anxiety. Lower quality of life, mortality and disability are independent outcomes of depression after stroke. CONCLUSION: Interventions for depression and its potential outcomes are required.
Authors: Anjail Z Sharrief; Brisa N Sánchez; Lynda D Lisabeth; Lesli E Skolarus; Darin B Zahuranec; Jonggyu Baek; Nelda Garcia; Erin Case; Lewis B Morgenstern Journal: J Stroke Cerebrovasc Dis Date: 2017-07-31 Impact factor: 2.136
Authors: Lesli E Skolarus; John D Piette; Paul N Pfeiffer; Linda S Williams; Jason Mackey; Rebecca Hughes; Lewis B Morgenstern Journal: Transl Stroke Res Date: 2016-07-09 Impact factor: 6.829
Authors: Ida Kim Wium-Andersen; Marie Kim Wium-Andersen; Martin Balslev Jørgensen; Merete Osler Journal: J Psychiatry Neurosci Date: 2017-09 Impact factor: 6.186
Authors: Fred Stephen Sarfo; Manolo Agbenorku; Sheila Adamu; Vida Obese; Patrick Berchie; Bruce Ovbiagele Journal: J Neurol Sci Date: 2019-07-23 Impact factor: 3.181
Authors: Lena M O'Keefe; Sarah J Doran; Laetitia Mwilambwe-Tshilobo; Lisa H Conti; Venugopal R Venna; Louise D McCullough Journal: Behav Brain Res Date: 2013-11-05 Impact factor: 3.332