Literature DB >> 23283061

Chronic human herpes virus 8 infection successfully treated with valganciclovir.

James J Yun1, Veronica Preda, Brad Frankum.   

Abstract

BACKGROUND: : A 57 year old Italian female with a 3 year history of constituitional symptoms with non-HIV Kaposi sarcoma was referred to the immunology clinic. She was previously diagnosed with chronic human herpes virus 8 (HHV8) infection with positive HHV8 polymerase chain reaction in serum.
OBJECTIVE: : Is valganciclovir effective in treating chronic human herpes virus 8 infection without Multicentric Castleman's Disease (MCD)?
RESULTS: : She was started on valganciclovir, resulting in remission of her symptoms, improvement in inflammatory markers and clearing of detectable HHV8 viraemia
CONCLUSION: : Valganciclovir is effective in treating symptomatic HHV8 infections without MCD.

Entities:  

Year:  2009        PMID： 23283061      PMCID： PMC3651015          DOI： 10.1097/WOX.0b013e3181abe7b6

Source DB:  PubMed          Journal:  World Allergy Organ J        ISSN： 1939-4551            Impact factor:   4.084


  6 in total

1.  A relapsing inflammatory syndrome and HHV-8.

Authors:  Ahmet Dogan; Ming-Qing Du; Peter G Isaacson
Journal:  N Engl J Med       Date:  2005-10-20       Impact factor: 91.245

2.  A relapsing inflammatory syndrome and active human herpesvirus 8 infection.

Authors:  Lorenzo Dagna; Francesco Broccolo; Carlo T Paties; Marina Ferrarini; Loredana Sarmati; Luisa Praderio; Maria Grazia Sabbadini; Paolo Lusso; Mauro S Malnati
Journal:  N Engl J Med       Date:  2005-07-14       Impact factor: 91.245

3.  Calibrated real-time PCR assay for quantitation of human herpesvirus 8 DNA in biological fluids.

Authors:  Francesco Broccolo; Giuseppe Locatelli; Loredana Sarmati; Sara Piergiovanni; Fabrizio Veglia; Massimo Andreoni; Stefano Buttò; Barbara Ensoli; Paolo Lusso; Mauro S Malnati
Journal:  J Clin Microbiol       Date:  2002-12       Impact factor: 5.948

4.  Valganciclovir for suppression of human herpesvirus-8 replication: a randomized, double-blind, placebo-controlled, crossover trial.

Authors:  Corey Casper; Elizabeth M Krantz; Lawrence Corey; Steven R Kuntz; Jie Wang; Stacy Selke; Shannon Hamilton; Meei-Li Huang; Anna Wald
Journal:  J Infect Dis       Date:  2008-07-01       Impact factor: 5.226

5.  Remission of HHV-8 and HIV-associated multicentric Castleman disease with ganciclovir treatment.

Authors:  Corey Casper; W Garrett Nichols; Meei-Li Huang; Lawrence Corey; Anna Wald
Journal:  Blood       Date:  2003-11-13       Impact factor: 22.113

6.  Primary human herpesvirus 8 infection generates a broadly specific CD8(+) T-cell response to viral lytic cycle proteins.

Authors:  Q J Wang; F J Jenkins; L P Jacobson; L A Kingsley; R D Day; Z W Zhang; Y X Meng; P E Pellett; K G Kousoulas; A Baghian; C R Rinaldo; P E Pellet
Journal:  Blood       Date:  2001-04-15       Impact factor: 22.113
  6 in total
  1 in total

1.  Kaposi Sarcoma in an Human Immunodeficiency Virus (HIV)-Seronegative Mediterranean Female: Report of a Rare Case.

Authors:  Marios Grigoriou; Konstantinia E Kofina; Aristeidis Ioannidis; Domniki K Gerasimidou; Christoforos Efthymiadis; Thomas Zaramboukas
Journal:  Am J Case Rep       Date:  2017-07-26
  1 in total

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