Literature DB >> 23282083

Aaptamine derivatives from the Indonesian sponge Aaptos suberitoides.

Cong-Dat Pham1, Rudolf Hartmann, Werner E G Müller, Nicole de Voogd, Daowan Lai, Peter Proksch.   

Abstract

Four new aaptamine derivatives (1-4) along with aaptamine (5) and three related compounds (6-8) were isolated from the ethanol extract of the sponge Aaptos suberitoides collected in Indonesia. The structures of the new compounds were unambiguously determined by one- and two-dimensional NMR and by HRESIMS measurements. Compounds 3, 5, and 6 showed cytotoxic activity against the murine lymphoma L5178Y cell line, with IC(50) values ranging from 0.9 to 8.3 μM.

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Year:  2013        PMID： 23282083     DOI： 10.1021/np300794b

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  6 in total

1.  Aaptamines, marine spongean alkaloids, as anti-dormant mycobacterial substances.

Authors:  Masayoshi Arai; Chisu Han; Yoshi Yamano; Andi Setiawan; Motomasa Kobayashi
Journal:  J Nat Med       Date:  2014-01-12       Impact factor: 2.343

2.  Callyspongiolide, a cytotoxic macrolide from the marine sponge Callyspongia sp.

Authors:  Cong-Dat Pham; Rudolf Hartmann; Philip Böhler; Björn Stork; Sebastian Wesselborg; Wenhan Lin; Daowan Lai; Peter Proksch
Journal:  Org Lett       Date:  2013-12-13       Impact factor: 6.005

3.  Aaptamine derivatives with antifungal and anti-HIV-1 activities from the South China Sea sponge Aaptos aaptos.

Authors:  Hao-Bing Yu; Fan Yang; Fan Sun; Jing Li; Wei-Hua Jiao; Jian-Hong Gan; Wen-Zhen Hu; Hou-Wen Lin
Journal:  Mar Drugs       Date:  2014-12-16       Impact factor: 5.118

4.  Antioxidant and UV-radiation absorption activity of aaptamine derivatives - potential application for natural organic sunscreens.

Authors:  Thi Le Anh Nguyen; Thi Hoai Nam Doan; Dinh Hieu Truong; Nguyen Thi Ai Nhung; Duong Tuan Quang; Dorra Khiri; Sonia Taamalli; Florent Louis; Abderrahman El Bakali; Duy Quang Dao
Journal:  RSC Adv       Date:  2021-06-17       Impact factor: 4.036

Review 5.  Marine Sponge Natural Products with Anticancer Potential: An Updated Review.

Authors:  Cinzia Calcabrini; Elena Catanzaro; Anupam Bishayee; Eleonora Turrini; Carmela Fimognari
Journal:  Mar Drugs       Date:  2017-10-13       Impact factor: 5.118

Review 6.  Chemical Diversity and Biological Activity of Secondary Metabolites Isolated from Indonesian Marine Invertebrates.

Authors:  Fauzia Izzati; Mega Ferdina Warsito; Asep Bayu; Anggia Prasetyoputri; Akhirta Atikana; Linda Sukmarini; Siti Irma Rahmawati; Masteria Yunovilsa Putra
Journal:  Molecules       Date:  2021-03-27       Impact factor: 4.411
  6 in total

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