Literature DB >> 23281513

Stem cells and spinal cord injury repair.

Soheila Karimi-Abdolrezaee1, Eftekhar Eftekharpour.   

Abstract

Spinal cord injury (SCI) has remained a challenging area for scientists and clinicians due to the adverse and complex nature of its pathobiology. To date, clinical therapies for debilitating SCI are largely ineffective. However, emerging research evidence suggests that repair of SCI can be promoted by stem cell-based therapies in regenerative medicine. Over the past decade, therapeutic potential of different types of stem cells for the treatment of SCI have been investigated in preclinical models. These studies have revealed multiple beneficial roles by which stem cells can improve the outcomes of SCI. This chapter will summarize the recent advances in the application of stem cells in regenerative medicine for the repair of SCI.

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Year:  2012        PMID: 23281513     DOI: 10.1007/978-1-4614-4090-1_4

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  10 in total

Review 1.  Microenvironmental regulation of oligodendrocyte replacement and remyelination in spinal cord injury.

Authors:  Arsalan Alizadeh; Soheila Karimi-Abdolrezaee
Journal:  J Physiol       Date:  2016-03-29       Impact factor: 5.182

2.  Anti-inflammatory and anti-apoptotic effect of combined treatment with methylprednisolone and amniotic membrane mesenchymal stem cells after spinal cord injury in rats.

Authors:  Shan Gao; Jie Ding; Hai-Jun Xiao; Zhi-Qiang Li; Yan Chen; Xing-Sheng Zhou; Jing-E Wang; Jiang Wu; Wei-Ze Shi
Journal:  Neurochem Res       Date:  2014-06-03       Impact factor: 3.996

3.  Anti-inflammatory Effect of Mesenchymal Stromal Cell Transplantation and Quercetin Treatment in a Rat Model of Experimental Cerebral Ischemia.

Authors:  Lan-Lan Zhang; Hong-Tian Zhang; Ying-Qian Cai; Yan-Jiang Han; Fang Yao; Zhao-Hu Yuan; Bing-Yi Wu
Journal:  Cell Mol Neurobiol       Date:  2016-03-23       Impact factor: 5.046

4.  Mild hypothermia combined with a scaffold of NgR-silenced neural stem cells/Schwann cells to treat spinal cord injury.

Authors:  Dong Wang; Jinhua Liang; Jianjun Zhang; Shuhong Liu; Wenwen Sun
Journal:  Neural Regen Res       Date:  2014-12-15       Impact factor: 5.135

5.  Tree shrew neural stem cell transplantation promotes functional recovery of tree shrews with a hemi‑sectioned spinal cord injury by upregulating nerve growth factor expression.

Authors:  Liu-Lin Xiong; Yu Zou; Yu Shi; Piao Zhang; Rong-Ping Zhang; Xie-Jie Dai; Bin Liu; Ting-Hua Wang
Journal:  Int J Mol Med       Date:  2018-03-09       Impact factor: 4.101

6.  Engraftment, neuroglial transdifferentiation and behavioral recovery after complete spinal cord transection in rats.

Authors:  Sabino Luzzi; Alberto Maria Crovace; Luca Lacitignola; Valerio Valentini; Edda Francioso; Giacomo Rossi; Gloria Invernici; Renato Juan Galzio; Antonio Crovace
Journal:  Surg Neurol Int       Date:  2018-01-25

7.  Human ex vivo spinal cord slice culture as a useful model of neural development, lesion, and allogeneic neural cell therapy.

Authors:  Chenhong Lin; Cinzia Calzarossa; Teresa Fernandez-Zafra; Jia Liu; Xiaofei Li; Åsa Ekblad-Nordberg; Erika Vazquez-Juarez; Simone Codeluppi; Lena Holmberg; Maria Lindskog; Per Uhlén; Elisabet Åkesson
Journal:  Stem Cell Res Ther       Date:  2020-07-29       Impact factor: 6.832

8.  Microelectrode arrays in combination with in vitro models of spinal cord injury as tools to investigate pathological changes in network activity: facts and promises.

Authors:  Miranda Mladinic; Andrea Nistri
Journal:  Front Neuroeng       Date:  2013-03-04

Review 9.  Myelin damage and repair in pathologic CNS: challenges and prospects.

Authors:  Arsalan Alizadeh; Scott M Dyck; Soheila Karimi-Abdolrezaee
Journal:  Front Mol Neurosci       Date:  2015-07-27       Impact factor: 5.639

Review 10.  Therapeutic repair for spinal cord injury: combinatory approaches to address a multifaceted problem.

Authors:  Jarred M Griffin; Frank Bradke
Journal:  EMBO Mol Med       Date:  2020-02-24       Impact factor: 12.137

  10 in total

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