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Literature DB >> 23281412

New approaches under development: cardiovascular embryology applied to heart disease.

Karl Degenhardt¹, Manvendra K Singh, Jonathan A Epstein.

Abstract

Despite many innovative advances in cardiology over the past 50 years, heart disease remains a major killer. The steady progress that continues to be made in diagnostics and therapeutics is offset by the cardiovascular consequences of the growing epidemics of obesity and diabetes. Truly innovative approaches on the horizon have been greatly influenced by new insights in cardiovascular development. In particular, research in stem cell biology, the cardiomyocyte lineage, and the interactions of the myocardium and epicardium have opened the door to new approaches for healing the injured heart.

Entities: Disease

Mesh：

Year: 2013 PMID： 23281412 PMCID： PMC3533277 DOI： 10.1172/JCI62884

Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808

52 in total

1. Distinct compartments of the proepicardial organ give rise to coronary vascular endothelial cells.

Authors: Tamar C Katz; Manvendra K Singh; Karl Degenhardt; José Rivera-Feliciano; Randy L Johnson; Jonathan A Epstein; Clifford J Tabin
Journal: Dev Cell Date: 2012-03-13 Impact factor: 12.270

2. Adult mouse epicardium modulates myocardial injury by secreting paracrine factors.

Authors: Bin Zhou; Leah B Honor; Huamei He; Qing Ma; Jin-Hee Oh; Catherine Butterfield; Ruei-Zeng Lin; Juan M Melero-Martin; Elena Dolmatova; Heather S Duffy; Alexander von Gise; Pingzhu Zhou; Yong Wu Hu; Gang Wang; Bing Zhang; Lianchun Wang; Jennifer L Hall; Marsha A Moses; Francis X McGowan; William T Pu
Journal: J Clin Invest Date: 2011-04-18 Impact factor: 14.808

3. A randomized trial of prenatal versus postnatal repair of myelomeningocele.

Authors: N Scott Adzick; Elizabeth A Thom; Catherine Y Spong; John W Brock; Pamela K Burrows; Mark P Johnson; Lori J Howell; Jody A Farrell; Mary E Dabrowiak; Leslie N Sutton; Nalin Gupta; Noel B Tulipan; Mary E D'Alton; Diana L Farmer
Journal: N Engl J Med Date: 2011-02-09 Impact factor: 91.245

4. Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency.

Authors: Frederick Anokye-Danso; Chinmay M Trivedi; Denise Juhr; Mudit Gupta; Zheng Cui; Ying Tian; Yuzhen Zhang; Wenli Yang; Peter J Gruber; Jonathan A Epstein; Edward E Morrisey
Journal: Cell Stem Cell Date: 2011-04-08 Impact factor: 24.633

Review 5. Pervasive roles of microRNAs in cardiovascular biology.

Authors: Eric M Small; Eric N Olson
Journal: Nature Date: 2011-01-20 Impact factor: 49.962

6. De novo cardiomyocytes from within the activated adult heart after injury.

Authors: Nicola Smart; Sveva Bollini; Karina N Dubé; Joaquim M Vieira; Bin Zhou; Sean Davidson; Derek Yellon; Johannes Riegler; Anthony N Price; Mark F Lythgoe; William T Pu; Paul R Riley
Journal: Nature Date: 2011-06-08 Impact factor: 49.962

7. Epicardium and myocardium separate from a common precursor pool by crosstalk between bone morphogenetic protein- and fibroblast growth factor-signaling pathways.

Authors: Bram van Wijk; Gert van den Berg; Radwan Abu-Issa; Phil Barnett; Saskia van der Velden; Martina Schmidt; Jan M Ruijter; Margaret L Kirby; Antoon F M Moorman; Maurice J B van den Hoff
Journal: Circ Res Date: 2009-07-23 Impact factor: 17.367

8. Cardiomyocyte renewal.

Authors: Michael S Parmacek; Jonathan A Epstein
Journal: N Engl J Med Date: 2009-07-02 Impact factor: 91.245

9. Retinoic acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration.

Authors: Kazu Kikuchi; Jennifer E Holdway; Robert J Major; Nicola Blum; Randall D Dahn; Gerrit Begemann; Kenneth D Poss
Journal: Dev Cell Date: 2011-03-15 Impact factor: 12.270

Review 3. "String theory" of c-kit(pos) cardiac cells: a new paradigm regarding the nature of these cells that may reconcile apparently discrepant results.

Authors: Matthew C L Keith; Roberto Bolli
Journal: Circ Res Date: 2015-03-27 Impact factor: 17.367

4. Cardiovascular science: opportunities for translating research into improved care.

Authors: Eugene Braunwald
Journal: J Clin Invest Date: 2013-01-02 Impact factor: 14.808

Review 5. The Hippo Signaling Pathway in Cardiac Development and Diseases.

Authors: Masum M Mia; Manvendra K Singh
Journal: Front Cell Dev Biol Date: 2019-10-01

5 in total