PURPOSE: We aim to derive an internationally applicable data set to improve prescription safety of psychiatric drugs. METHODS: We performed an in-depth analysis of the concordance of prescribing information of 10 key psychiatric drugs across four major drug markets with regard to indications, warnings and precautions, and contraindications. RESULTS: The individual prescribing information covered on average 71.4 ± 30.3% of all named indications, 59.5 ± 17.1% of all potential warnings and precautions and 70.1 ± 24.4% of all applicable contraindications. CONCLUSION: This substantial variation in key prescribing information across countries highlights the need for a better international cooperation and standardization of prescribing information.
PURPOSE: We aim to derive an internationally applicable data set to improve prescription safety of psychiatric drugs. METHODS: We performed an in-depth analysis of the concordance of prescribing information of 10 key psychiatric drugs across four major drug markets with regard to indications, warnings and precautions, and contraindications. RESULTS: The individual prescribing information covered on average 71.4 ± 30.3% of all named indications, 59.5 ± 17.1% of all potential warnings and precautions and 70.1 ± 24.4% of all applicable contraindications. CONCLUSION: This substantial variation in key prescribing information across countries highlights the need for a better international cooperation and standardization of prescribing information.
Authors: Laura Weisbach; Anna K Schuster; Michael Hartmann; Martin F Fromm; Renke Maas; Katrin Farker Journal: J Clin Med Date: 2022-03-30 Impact factor: 4.241