BACKGROUND: Lead toxicity is a prevalent health problem in both developed and developing countries. One of the proposed mechanisms for lead-induced organ damage is oxidative stress. Oxidative stress is well-associated with the pregnancy disorder, pre-eclampsia. Exposure to lead may be one of the sources of the oxidative stress that leads to development of pre-eclampsia in pregnant women. OBJECTIVE: To test if blood lead level of pregnant women suffering from pre-eclampsia is higher than the normal limit. METHODS: Using atomic absorption spectrophotometry, blood lead level was measured in 115 pregnant women suffering from pre-eclampsia and compared to its level in a comparison group of 25 healthy pregnant women in Dakahlia governorate, Egypt. RESULTS: The mean±SD blood lead level was 37.68±9.17 μg/dL in women with pre-eclampsia; the value in the comparison group was 14.5±3.18 μg/dL (p<0.001). CONCLUSION: Pre-eclampsia is significantly associated with a high blood lead level.
BACKGROUND: Lead toxicity is a prevalent health problem in both developed and developing countries. One of the proposed mechanisms for lead-induced organ damage is oxidative stress. Oxidative stress is well-associated with the pregnancy disorder, pre-eclampsia. Exposure to lead may be one of the sources of the oxidative stress that leads to development of pre-eclampsia in pregnant women. OBJECTIVE: To test if blood lead level of pregnant women suffering from pre-eclampsia is higher than the normal limit. METHODS: Using atomic absorption spectrophotometry, blood lead level was measured in 115 pregnant women suffering from pre-eclampsia and compared to its level in a comparison group of 25 healthy pregnant women in Dakahlia governorate, Egypt. RESULTS: The mean±SD blood lead level was 37.68±9.17 μg/dL in women with pre-eclampsia; the value in the comparison group was 14.5±3.18 μg/dL (p<0.001). CONCLUSION: Pre-eclampsia is significantly associated with a high blood lead level.
Authors: Thomas Rduch; Elena Tsolaki; Yassir El Baz; Sebastian Leschka; Diana Born; Janis Kinkel; Alexandre H C Anthis; Tina Fischer; Wolfram Jochum; René Hornung; Alexander Gogos; Inge K Herrmann Journal: Front Med (Lausanne) Date: 2022-03-30
Authors: Katarzyna Gajewska; Marzena Laskowska; Agostinho Almeida; Edgar Pinto; Katarzyna Skórzyńska-Dziduszko; Anna Błażewicz Journal: Molecules Date: 2021-05-20 Impact factor: 4.411