Literature DB >> 23279429

BACE1 influences debris clearance and axonal regeneration in injured peripheral nerve.

Mohamed H Farah1.   

Abstract

During 3 years, my research activities in Jack Griffin's laboratory focused on the influence of β-amyloid precursor protein cleaving enzyme 1 (BACE1) on the degeneration/regeneration of sciatic nerve of mice. Here, potential mechanisms of how BACE1 enzymatic activity influences these processes are discussed.
© 2012 Peripheral Nerve Society.

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Year:  2012        PMID: 23279429     DOI: 10.1111/j.1529-8027.2012.00428.x

Source DB:  PubMed          Journal:  J Peripher Nerv Syst        ISSN: 1085-9489            Impact factor:   3.494


  3 in total

1.  Paclitaxel causes degeneration of both central and peripheral axon branches of dorsal root ganglia in mice.

Authors:  Aniqa Tasnim; Zoe Rammelkamp; Amy B Slusher; Krystyna Wozniak; Barbara S Slusher; Mohamed H Farah
Journal:  BMC Neurosci       Date:  2016-07-11       Impact factor: 3.288

Review 2.  Beta secretase activity in peripheral nerve regeneration.

Authors:  Carolyn Tallon; Mohamed H Farah
Journal:  Neural Regen Res       Date:  2017-10       Impact factor: 5.135

3.  Asparagine Endopeptidase (δ Secretase), an Enzyme Implicated in Alzheimer's Disease Pathology, Is an Inhibitor of Axon Regeneration in Peripheral Nerves.

Authors:  Arthur W English; Xia Liu; Olivia C Mistretta; Patricia J Ward; Keqiang Ye
Journal:  eNeuro       Date:  2021-01-15
  3 in total

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