| Literature DB >> 2327898 |
T Horimoto1, J A Limcumpao, Y Tohya, E Takahashi, T Mikami.
Abstract
Monoclonal antibodies (MoAbs) to feline herpesvirus type 1 (FHV-1) were produced to identify the virus-specified immunogenic proteins. When antigens recognized by the MoAbs were investigated by immunoblot and immunoprecipitation assays using FHV-1-infected cell lysate, four groups of immunogenic proteins were identified. MoAbs directed against 60 kDa, 113 kDa, and 143 kDa/108 kDa glycoproteins had virus neutralizing activities, but those against 170 kDa protein did not. Furthermore, MoAbs to the 60 kDa glycoprotein also showed hemagglutination-inhibition activity, indicating that this glycoprotein might be the hemagglutinin.Entities:
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Year: 1990 PMID: 2327898 DOI: 10.1007/bf01310510
Source DB: PubMed Journal: Arch Virol ISSN: 0304-8608 Impact factor: 2.574