Literature DB >> 23276765

Adrenal incidentaloma does it require surgical treatment? Case report and review of literature.

Gurushantappa H Yalagachin1, Bharath Kumar Bhat.   

Abstract

INTRODUCTION: Adrenal incidentalomas have a prevalence of at least 5% in the general population. Among these adrenal myelolipoma are rare nonfunctioning tumors of adrenal with an incidence of 0.1-0.2% as documented in CT and autopsy series. We report such a rare case of adrenal myelolipoma incidentally detected while evaluating a case of chronic nonspecific flank pain. PRESENTATION OF CASE: 38-year-old obese female patient, known hypertensive on treatment presented with nonspecific right flank pain since 1 year. Ultrasonography and Computed tomography of the abdomen showed right adrenal gland mass with fat density measuring 6.3cm×6.2cm×5cm. Patient underwent right side adrenalectomy, post operatively patient had an uneventful recovery. Histopathological examination of the specimen revealed features of adrenal myelolipoma. DISCUSSION: Myelolipoma is an uncommon, benign; tumor like lesion composed of mature adipose tissue admixed with hematopoietic cells. Most myelolipomas appear as unilateral adrenal masses. Adrenal myelolipomas are usually small and asymptomatic. CT or MRI detects the areas of gross fat with in the lesion. These tumors can present as acute abdomen following tumor hemorrhage which is more likely in myelolipomas greater than 4cm in size, hence warrants adrenalectomy.
CONCLUSION: adrenal myelolipoma are rare benign tumors, incidentally detected on CT. CT or MRI is diagnostic. Large myelolipoma warrants surgery due to the risk of hemorrhage.
Copyright © 2012 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

Entities:  

Year:  2012        PMID: 23276765      PMCID: PMC3540227          DOI: 10.1016/j.ijscr.2012.09.014

Source DB:  PubMed          Journal:  Int J Surg Case Rep        ISSN: 2210-2612


  6 in total

Review 1.  Adrenal myelolipoma: a 10-year single-center experience and literature review.

Authors:  Sz-Wen Hsu; Kenneth Shu; Wei-Ching Lee; Yuan-Tso Cheng; Po-Hui Chiang
Journal:  Kaohsiung J Med Sci       Date:  2012-04-28       Impact factor: 2.744

2.  Adrenal myelolipomas show nonrandom X-chromosome inactivation in hematopoietic elements and fat: support for a clonal origin of myelolipomas.

Authors:  Elena Bishop; John N Eble; Liang Cheng; Mingsheng Wang; Donald R Chase; Attilio Orazi; Dennis P O'Malley
Journal:  Am J Surg Pathol       Date:  2006-07       Impact factor: 6.394

3.  Imaging and pathologic features of myelolipoma.

Authors:  P Rao; P J Kenney; B J Wagner; A J Davidson
Journal:  Radiographics       Date:  1997 Nov-Dec       Impact factor: 5.333

4.  Myelolipoma of the adrenal gland.

Authors:  H Ishikawa; M Tachibana; M Hata; H Tazaki; S Akatsuka; H Iri
Journal:  J Urol       Date:  1981-12       Impact factor: 7.450

5.  The incidental adrenal mass on CT: prevalence of adrenal disease in 1,049 consecutive adrenal masses in patients with no known malignancy.

Authors:  Julie H Song; Fakhra S Chaudhry; William W Mayo-Smith
Journal:  AJR Am J Roentgenol       Date:  2008-05       Impact factor: 3.959

6.  Myelolipoma: an unusual surgical lesion of the adrenal gland.

Authors:  M J Noble; D K Montague; H S Levin
Journal:  Cancer       Date:  1982-03-01       Impact factor: 6.860

  6 in total
  5 in total

1.  Adrenal Myelolipoma Mimics Ectopic Adrenal or Renal Tissue: An Incidental Finding During Cadaveric Dissection.

Authors:  R K Narayan; A Asghar; S K Ghosh; S Bharti
Journal:  Acta Endocrinol (Buchar)       Date:  2021 Apr-Jun       Impact factor: 0.877

2.  A RARE CASE OF RAPIDLY ENLARGING MYELOLIPOMA IN SICKLE CELL DISEASE.

Authors:  Paran Davari; Cortney Youens Lee; James Te-An Lee
Journal:  AACE Clin Case Rep       Date:  2020-12-20

3.  Bilateral adrenal hemorrhage in a patient with myelodysplastic syndrome: value of MRI in the differential diagnosis.

Authors:  Lucia Manganaro; Najwa Al Ansari; Flavio Barchetti; Matteo Saldari; Claudia Vitturini; Marianna Glorioso; Valeria Buonocore; Giovanni Barchetti; Francesca Maccioni
Journal:  Case Rep Radiol       Date:  2013-12-05

4.  Adrenal extramedullary hematopoiesis associated with beta-thalassemia trait in an adult woman: a case report and review of literature.

Authors:  Hassan Al-Thani; Maryam Al-Sulaiti; Gamela El-Mabrok; AbdelHakim Tabeb; Ayman El-Menyar
Journal:  Int J Surg Case Rep       Date:  2016-05-19

5.  Case Report: An incidentaloma that catches your eye - adrenal myelolipoma.

Authors:  Rosanna D'Addosio; Joselyn Rojas; Valmore Bermúdez; Flor Ledesma; Kyle Hoedebecke
Journal:  F1000Res       Date:  2017-07-18
  5 in total

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