Literature DB >> 23275902

Effect of simulated dynamic intraocular pressure on retinal thickness measured by optical coherence tomography after cataract surgery.

Ding Chen1, Jun Zhu, Jin Li, Xi-Xia Ding, Fan Lu, Yun-E Zhao.   

Abstract

AIM: To investigate the effect of simulated dynamic intraocular pressure (SDIOP) during uncomplicated phacoemulsification on postoperative macular and peripapillary retinal nerve fiber layer (RNFL) thickness.
METHODS: Macular and RNFL thicknesses in one eye of patients (n=30) undergoing uncomplicated phacoemulsification were measured by optical coherence tomography preoperatively and 1 week postoperatively. The best-corrected visual acuity, SDIOP, irrigation time (IT), effective phacoemulsification time, entire surgical duration, blood pressure, and heart rate were recorded.
RESULTS: The mean SDIOP and IT was (74.9 ± 27.4)cmH(2)O and (178.4 ± 21.6) seconds respectively. We divided our patients into two groups based upon IT with greater than 90cmH(2)O (P(>90)IT). In Group A (n=14), the P(>90)IT was greater than the mean P(>90)IT, and in Group B (n=16), the P(>90)IT was less than the mean P(>90)IT. For all patients there was a significant increase in macular thickness one week after cataract surgery (P=0.001). While the RNFL thickness tended to increase, the change was not significant. The postoperative macular thickness of Group A, (277.8 ± 13.7)µm, was significantly thicker than that of Group B, (267.9 ± 15.0)µm (P=0.004). The postoperative peripapillary RNFL thickness of Group A, (96.8 ± 10.8) µm, was not significantly different from Group B. For Group A, the change in macular thickness was positively correlated with P(>90)IT (R(2)=0.524, P=0.02). There was no statistical difference in postoperative visual acuity between Groups A and B.
CONCLUSION: After uncomplicated phacoemulsification, increased macular thickness is associated with the IT under high SDIOP. The effect of high SDIOP is limited to the sub-clinical level.

Entities:  

Keywords:  intraocular pressure; optical coherence tomography; phacoemulsification; retina

Year:  2012        PMID: 23275902      PMCID: PMC3530809          DOI: 10.3980/j.issn.2222-3959.2012.06.07

Source DB:  PubMed          Journal:  Int J Ophthalmol        ISSN: 2222-3959            Impact factor:   1.779


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