Literature DB >> 23275849

Presentation of Epilepsy in a Patient with Wilson's Disease and Developmental Venous Anomaly (Venous Angioma) in the Brain.

Ammar Alobaidy1, Faisal Alazri, P C Jacob, Jamila H Al-Kalbani.   

Abstract

Intracranial developmental venous anomalies (DVAs), also called venous angiomas, and Wilson's disease are both considered rare disorders with varying degrees of neurologic and systemic manifestations; yet the coexistence of the two disorders is considered extremely rare, bearing in mind the low prevalence of each disorder. Epilepsy is a recognised presentation in these disorders and will be the focus of discussion in our report of a 21-year-old male patient who, based on a clinical examination and laboratory and neuroimaging results, was diagnosed with both Wilson's disease and DVA. He presented initially at Sultan Qaboos University Hospital, Oman with tremors and writing difficulties in the right hand followed by the development of epilepsy, and was treated medically by de-coppering and antiepileptic medications. We also present a brief literature review of both disorders, their association with epilepsy, and treatment options. Family screening for patients with Wilson's disease is pivotal in preventing unfavourable outcomes.

Entities:  

Keywords:  Case report; Epilepsy; Intracranial venous angioma; Oman; Wilson’s disease

Year:  2012        PMID: 23275849      PMCID: PMC3524002          DOI: 10.12816/0003178

Source DB:  PubMed          Journal:  Sultan Qaboos Univ Med J        ISSN: 2075-051X


  13 in total

1.  Pathomechanisms of symptomatic developmental venous anomalies.

Authors:  Vitor M Pereira; Sasikhan Geibprasert; Timo Krings; Thaweesak Aurboonyawat; Augustin Ozanne; Frederique Toulgoat; Sirintara Pongpech; Pierre L Lasjaunias
Journal:  Stroke       Date:  2008-11-06       Impact factor: 7.914

Review 2.  Cerebral developmental venous anomalies: current concepts.

Authors:  Diego San Millán Ruíz; Hasan Yilmaz; Philippe Gailloud
Journal:  Ann Neurol       Date:  2009-09       Impact factor: 10.422

3.  MR evaluation of developmental venous anomalies: medullary venous anatomy of venous angiomas.

Authors:  C Lee; M A Pennington; C M Kenney
Journal:  AJNR Am J Neuroradiol       Date:  1996-01       Impact factor: 3.825

4.  The caput medusae sign.

Authors:  P R Saba
Journal:  Radiology       Date:  1998-06       Impact factor: 11.105

Review 5.  Intracranial developmental venous anomalies: diagnosis using CT angiography.

Authors:  T R Peebles; P T Vieco
Journal:  J Comput Assist Tomogr       Date:  1997 Jul-Aug       Impact factor: 1.826

Review 6.  Wilson's disease and epilepsy.

Authors:  T R Dening; G E Berrios; J M Walshe
Journal:  Brain       Date:  1988-10       Impact factor: 13.501

7.  Venous angiomas: an underestimated cause of intracranial hemorrhage.

Authors:  G M Malik; J K Morgan; R S Boulos; J I Ausman
Journal:  Surg Neurol       Date:  1988-11

8.  The natural history of intracranial venous angiomas.

Authors:  T B Garner; O Del Curling; D L Kelly; D W Laster
Journal:  J Neurosurg       Date:  1991-11       Impact factor: 5.115

9.  Cerebral developmental venous anomalies associated with head and neck venous malformations.

Authors:  M Boukobza; O Enjolras; J P Guichard; F Gelbert; D Herbreteau; D Reizine; J J Merland
Journal:  AJNR Am J Neuroradiol       Date:  1996-05       Impact factor: 3.825

10.  Levetiracetam in the treatment of epilepsy.

Authors:  Bassel Abou-Khalil
Journal:  Neuropsychiatr Dis Treat       Date:  2008-06       Impact factor: 2.570

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