Literature DB >> 23274457

Fragment-based lead discovery grows up.

Monya Baker.   

Abstract

Mesh：

Year:  2013        PMID： 23274457     DOI： 10.1038/nrd3926

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  49 in total

1.  The 'rule of three' for fragment-based drug discovery: where are we now?

Authors:  Harren Jhoti; Glyn Williams; David C Rees; Christopher W Murray
Journal:  Nat Rev Drug Discov       Date:  2013-07-12       Impact factor: 84.694

2.  The importance of molecular complexity in the design of screening libraries.

Authors:  Shahul H Nilar; Ngai Ling Ma; Thomas H Keller
Journal:  J Comput Aided Mol Des       Date:  2013-09       Impact factor: 3.686

3.  A three-stage biophysical screening cascade for fragment-based drug discovery.

Authors:  Ellene H Mashalidis; Paweł Śledź; Steffen Lang; Chris Abell
Journal:  Nat Protoc       Date:  2013-10-24       Impact factor: 13.491

4.  Fragment-based strategy for structural optimization in combination with 3D-QSAR.

Authors:  Haoliang Yuan; Wenting Tai; Shihe Hu; Haichun Liu; Yanmin Zhang; Sihui Yao; Ting Ran; Shuai Lu; Zhipeng Ke; Xiao Xiong; Jinxing Xu; Yadong Chen; Tao Lu
Journal:  J Comput Aided Mol Des       Date:  2013-11-01       Impact factor: 3.686

Review 5.  Evolutions in fragment-based drug design: the deconstruction-reconstruction approach.

Authors:  Haijun Chen; Xiaobin Zhou; Ailan Wang; Yunquan Zheng; Yu Gao; Jia Zhou
Journal:  Drug Discov Today       Date:  2014-09-27       Impact factor: 7.851

6.  Fragment virtual screening based on Bayesian categorization for discovering novel VEGFR-2 scaffolds.

Authors:  Yanmin Zhang; Yu Jiao; Xiao Xiong; Haichun Liu; Ting Ran; Jinxing Xu; Shuai Lu; Anyang Xu; Jing Pan; Xin Qiao; Zhihao Shi; Tao Lu; Yadong Chen
Journal:  Mol Divers       Date:  2015-05-29       Impact factor: 2.943

7.  Identification of potential glutaminyl cyclase inhibitors from lead-like libraries by in silico and in vitro fragment-based screening.

Authors:  Mária Szaszkó; István Hajdú; Beáta Flachner; Krisztina Dobi; Csaba Magyar; István Simon; Zsolt Lőrincz; Zoltán Kapui; Tamás Pázmány; Sándor Cseh; György Dormán
Journal:  Mol Divers       Date:  2017-01-09       Impact factor: 2.943

Review 8.  Fragment-based inhibitor discovery against β-lactamase.

Authors:  Derek A Nichols; Adam R Renslo; Yu Chen
Journal:  Future Med Chem       Date:  2014-03       Impact factor: 3.808

Review 9.  Therapeutic Potential of Spirooxindoles as Antiviral Agents.

Authors:  Na Ye; Haiying Chen; Eric A Wold; Pei-Yong Shi; Jia Zhou
Journal:  ACS Infect Dis       Date:  2016-05-05       Impact factor: 5.084

10.  Statistical removal of background signals from high-throughput (1)H NMR line-broadening ligand-affinity screens.

Authors:  Bradley Worley; Nicholas J Sisco; Robert Powers
Journal:  J Biomol NMR       Date:  2015-07-09       Impact factor: 2.835
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