Literature DB >> 23273795

Controversies in conventional radiography in spondyloarthritis.

Walter P Maksymowych1.   

Abstract

Radiographic assessment of spondyloarthritis constitutes the primary imaging modality for diagnostic evaluation although it is insensitive in early disease. Several years are required before definite changes can be seen in the sacroiliac joints, and magnetic resonance imaging is the preferred imaging modality when the clinical presentation suggests spondyloarthritis but the pelvic radiograph is normal or equivocal. There is little evidence that special views of the sacroiliac joints or a series of views depicting the joint are superior to a conventional antero-posterior radiograph. Studies in early disease suggest that only 30-60% of patients diagnosed with axial spondyloarthritis on clinical grounds have definite radiographic sacroiliitis. Prospective study is required for further clarity on the role of radiography in early disease. Several scoring methods have been described for the quantitative assessment of radiographic changes in the spine and hips. These methods can be used for staging of disease as well as for assessing progression in clinical trials and prognostic studies. The modified Stoke Ankylosing Spondylitis Spine Score is the preferred method for assessing progression because of its superior sensitivity to change. Nevertheless, the amount of change detected is limited, even after 2 years of follow-up, and this requires further standardisation of methodology before widespread implementation of this method.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID: 23273795     DOI: 10.1016/j.berh.2012.10.003

Source DB:  PubMed          Journal:  Best Pract Res Clin Rheumatol        ISSN: 1521-6942            Impact factor:   4.098


  4 in total

1.  Value of dedicated small-field-of-view sacroiliac versus large-field-of-view pelvic magnetic resonance imaging for evaluating pediatric sacroiliitis.

Authors:  Sagar Wagle; Jeff T Gu; Jesse L Courtier; Andrew S Phelps; Clara Lin; John D MacKenzie
Journal:  Pediatr Radiol       Date:  2019-01-08

Review 2.  Improving the design of RCTs in non-radiographic axial spondyloarthritis.

Authors:  Walter P Maksymowych; Robert G W Lambert; Liron Caplan; Filip E van den Bosch; Mikkel Østergaard
Journal:  Nat Rev Rheumatol       Date:  2022-05-13       Impact factor: 32.286

3.  The FAt Spondyloarthritis Spine Score (FASSS): development and validation of a new scoring method for the evaluation of fat lesions in the spine of patients with axial spondyloarthritis.

Authors:  Susanne Juhl Pedersen; Zheng Zhao; Robert G W Lambert; Stephanie Wichuk; Mikkel Østergaard; Ulrich Weber; Walter P Maksymowych
Journal:  Arthritis Res Ther       Date:  2013       Impact factor: 5.156

4.  Evaluation of the change in structural radiographic sacroiliac joint damage after 2 years of etanercept therapy (EMBARK trial) in comparison to a contemporary control cohort (DESIR cohort) in recent onset axial spondyloarthritis.

Authors:  Maxime Dougados; Walter P Maksymowych; Robert B M Landewé; Anna Moltó; Pascal Claudepierre; Manouk de Hooge; Robert G Lambert; Randi Bonin; Jack F Bukowski; Heather E Jones; Isabelle Logeart; Ron Pedersen; Annette Szumski; Bonnie Vlahos; Désirée van der Heijde
Journal:  Ann Rheum Dis       Date:  2017-09-29       Impact factor: 19.103

  4 in total

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