Literature DB >> 2327301

Lipid A, the immunostimulatory principle of lipopolysaccharides?

H Loppnow1, I Dürrbaum, H Brade, C A Dinarello, S Kusumoto, E T Rietschel, H D Flad.   

Abstract

Lipid A has been found to be an inducer of IL-1 with similar potency as LPS. Partial structures of lipid A or core oligosaccharides are less active or not active at all. We propose that lipid A is the structure responsible for induction of immunostimulatory or immunoregulatory properties of LPS.

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Year:  1990        PMID: 2327301     DOI: 10.1007/978-1-4757-5140-6_50

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  3 in total

Review 1.  Contribution of Porphyromonas gingivalis lipopolysaccharide to periodontitis.

Authors:  Sumita Jain; Richard P Darveau
Journal:  Periodontol 2000       Date:  2010-10       Impact factor: 7.589

2.  Characterization of WRSs2 and WRSs3, new second-generation virG(icsA)-based Shigella sonnei vaccine candidates with the potential for reduced reactogenicity.

Authors:  S Barnoy; K I Jeong; R F Helm; A E Suvarnapunya; R T Ranallo; S Tzipori; M M Venkatesan
Journal:  Vaccine       Date:  2009-11-20       Impact factor: 3.641

Review 3.  Periodontitis and cardiometabolic disorders: The role of lipopolysaccharide and endotoxemia.

Authors:  Pirkko J Pussinen; Elisa Kopra; Milla Pietiäinen; Markku Lehto; Svetislav Zaric; Susanna Paju; Aino Salminen
Journal:  Periodontol 2000       Date:  2022-03-04       Impact factor: 12.239

  3 in total

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