Literature DB >> 23270991

Antivirals: past, present and future.

Erik De Clercq1.   

Abstract

Vaccination is possible to prevent infections with some viruses: hepatitis B virus (HBV), varicella-zoster virus (VZV), influenza A and B viruses, Yellow fever virus and poliovirus; but not for others: human immunodeficiency virus (HIV), hepatitis C virus (HCV), herpes simplex virus (HSV), cytomegalovirus (CMV), and most hemorrhagic fever viruses (HFV) (except for Yellow fever virus). Antiviral therapy is obviously needed to control those infections that are not amenable to prophylaxis by vaccination, but is also highly desirable for those infections where vaccination has not been implemented or did not fulfill its premises for complete protection.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2012        PMID： 23270991     DOI： 10.1016/j.bcp.2012.12.011

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN： 0006-2952            Impact factor:   5.858


  27 in total

1.  Rapamycin modulation of p70 S6 kinase signaling inhibits Rift Valley fever virus pathogenesis.

Authors:  Todd M Bell; Virginia Espina; Svetlana Senina; Caitlin Woodson; Ashwini Brahms; Brian Carey; Shih-Chao Lin; Lindsay Lundberg; Chelsea Pinkham; Alan Baer; Claudius Mueller; Elizabeth A Chlipala; Faye Sharman; Cynthia de la Fuente; Lance Liotta; Kylene Kehn-Hall
Journal:  Antiviral Res       Date:  2017-04-23       Impact factor: 5.970

Review 2.  Approved Antiviral Drugs over the Past 50 Years.

Authors:  Erik De Clercq; Guangdi Li
Journal:  Clin Microbiol Rev       Date:  2016-07       Impact factor: 26.132

3.  Sophoridine Suppresses Herpes Simplex Virus Type 1 Infection by Blocking the Activation of Cellular PI3K/Akt and p38 MAPK Pathways.

Authors:  Qiong Tang; Fei Luan; An Yuan; Jiayi Sun; Zhili Rao; Baojun Wang; Yao Liu; Nan Zeng
Journal:  Front Microbiol       Date:  2022-06-10       Impact factor: 6.064

4.  Design, synthesis, and mechanistic investigations of phenylalanine derivatives containing a benzothiazole moiety as HIV-1 capsid inhibitors with improved metabolic stability.

Authors:  Shujing Xu; Lin Sun; Alexej Dick; Waleed A Zalloum; Tianguang Huang; Megan E Meuser; Xujie Zhang; Yucen Tao; Srinivasulu Cherukupalli; Dang Ding; Xiao Ding; Shenghua Gao; Xiangyi Jiang; Dongwei Kang; Erik De Clercq; Christophe Pannecouque; Simon Cocklin; Xinyong Liu; Peng Zhan
Journal:  Eur J Med Chem       Date:  2021-10-09       Impact factor: 7.088

5.  Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities.

Authors:  Lin Sun; Alexej Dick; Megan E Meuser; Tianguang Huang; Waleed A Zalloum; Chin-Ho Chen; Srinivasulu Cherukupalli; Shujing Xu; Xiao Ding; Ping Gao; Dongwei Kang; Erik De Clercq; Christophe Pannecouque; Simon Cocklin; Kuo-Hsiung Lee; Xinyong Liu; Peng Zhan
Journal:  J Med Chem       Date:  2020-04-29       Impact factor: 7.446

6.  The connection domain mutation N348I in HIV-1 reverse transcriptase enhances resistance to etravirine and rilpivirine but restricts the emergence of the E138K resistance mutation by diminishing viral replication capacity.

Authors:  Hong-Tao Xu; Susan P Colby-Germinario; Maureen Oliveira; Yingshan Han; Yudong Quan; Veronica Zanichelli; Mark A Wainberg
Journal:  J Virol       Date:  2013-11-13       Impact factor: 5.103

7.  Design, synthesis, and antiviral activity of phenylalanine derivatives as HIV-1 capsid inhibitors.

Authors:  Jing Li; Xiangyi Jiang; Alexej Dick; Prem Prakash Sharma; Chin-Ho Chen; Brijesh Rathi; Dongwei Kang; Zhao Wang; Xiangkai Ji; Kuo-Hsiung Lee; Simon Cocklin; Xinyong Liu; Peng Zhan
Journal:  Bioorg Med Chem       Date:  2021-09-17       Impact factor: 3.461

8.  Anti HSV-1 activity of halistanol sulfate and halistanol sulfate C isolated from Brazilian marine sponge Petromica citrina (Demospongiae).

Authors:  Tatiana da Rosa Guimarães; Carlos Guillermo Quiroz; Caroline Rigotto Borges; Simone Quintana de Oliveira; Maria Tereza Rojo de Almeida; Éverson Miguel Bianco; Maria Izabel Goulart Moritz; João Luís Carraro; Jorge Alejandro Palermo; Gabriela Cabrera; Eloir Paulo Schenkel; Flávio Henrique Reginatto; Cláudia Maria Oliveira Simões
Journal:  Mar Drugs       Date:  2013-10-29       Impact factor: 5.118

9.  Compelling Evidence for the Activity of Antiviral Peptides against SARS-CoV-2.

Authors:  Miray Tonk; Daniel Růžek; Andreas Vilcinskas
Journal:  Viruses       Date:  2021-05-14       Impact factor: 5.048

10.  Herpes zoster vaccination.

Authors:  Kyung Hoon Kim
Journal:  Korean J Pain       Date:  2013-07-01
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