Literature DB >> 23270499

cis-Decahydroquinolines via asymmetric organocatalysis: application to the total synthesis of lycoposerramine Z.

Ben Bradshaw1, Carlos Luque-Corredera, Josep Bonjoch.   

Abstract

A concise synthesis of the Lycopodium alkaloid lycoposerramine Z is reported. Key to the strategy is a one-pot organocatalyzed Michael reaction followed by a domino Robinson annulation/intramolecular aza-Michael reaction promoted by LiOH, leading to enantiopure cis-decahydroquinolines.

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Year:  2012        PMID： 23270499     DOI： 10.1021/ol303257y

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  Synthesis of cis-hydrindan-2,4-diones bearing an all-carbon quaternary center by a Danheiser annulation.

Authors:  Gisela V Saborit; Carlos Cativiela; Ana I Jiménez; Josep Bonjoch; Ben Bradshaw
Journal:  Beilstein J Org Chem       Date:  2018-10-09       Impact factor: 2.883

Review 2.  Advances in the Asymmetric Total Synthesis of Natural Products Using Chiral Secondary Amine Catalyzed Reactions of α,β-Unsaturated Aldehydes.

Authors:  Zhonglei Wang
Journal:  Molecules       Date:  2019-09-19       Impact factor: 4.411
  2 in total

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