Literature DB >> 23269706

Ovarian fibromas and fibrothecomas: sonographic correlation with computed tomography and magnetic resonance imaging: a 5-year single-institution experience.

Philip Yen1, Kathleen Khong, Ramit Lamba, Michael T Corwin, Eugenio O Gerscovich.   

Abstract

OBJECTIVES: To evaluate imaging characteristics of ovarian fibromas and fibrothecomas and to identify select clinical markers and imaging features to help in their diagnosis.
METHODS: Over a 5-year period, 18 of 29 women with histologically proven fibromas or fibrothecomas underwent sonography, computed tomography (CT), or magnetic resonance imaging (MRI). On review of the images, tumor size, solid component characteristics, and cystic components were evaluated. Age, cancer antigen 125 (CA-125), and Meig syndrome were assessed.
RESULTS: Eleven fibrothecomas and 7 fibromas were evaluated. Sonography was performed for 15 tumors, CT for 9, and MRI for 6. Mean age was 52.6 (range, 13-82) years. Mean tumor size was 8.8 (range, 2-18) cm. Seventy-two percent of the tumors were solid, and 28% had cystic components. On sonography, the solid components were isoechoic or hypoechoic compared to the uterus. On CT with contrast, 2 of 8 lesions (25%) showed enhancement. On T1-weighted MRI, 5 lesions (83%) showed an isointense signal, and 1 (17%) showed a hyperintense signal compared to the myometrium. On T2-weighted MRI, 4 of 6 lesions (67%) were hypointense; 1 (16.5%) was isointense; and 1 (16.5%) was hyperintense. Elevated CA-125 was present in 5 of 29 patients (28%). One had Meig syndrome.
CONCLUSIONS: For a cystic adnexal mass where the primary consideration is commonly an epithelial tumor, the possibility of a cystic stromal tumor should also be considered. Unlike previous studies reporting both T1 and T2 hypointensity, fibrothecomas and fibromas can also show T1 and T2 isointensity and, exceptionally, hyperintensity. Vascularity, shown by Doppler flow and MRI and CT enhancement, is a characteristic of some fibromas and fibrothecomas. Although CA-125 is elevated in some patients, a true correlation is difficult to assess. Meig syndrome is infrequent.

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Year:  2013        PMID: 23269706     DOI: 10.7863/jum.2013.32.1.13

Source DB:  PubMed          Journal:  J Ultrasound Med        ISSN: 0278-4297            Impact factor:   2.153


  9 in total

1.  Computed tomography and magnetic resonance imaging features of ovarian fibrothecoma.

Authors:  Jingya Chen; Jianhua Wang; Xiao Chen; Yaohui Wang; Zhongqiu Wang; Dake Li
Journal:  Oncol Lett       Date:  2017-05-22       Impact factor: 2.967

Review 2.  Sex cord-stromal tumors of the ovary: a comprehensive review and update for radiologists.

Authors:  Mariana Horta; Teresa Margarida Cunha
Journal:  Diagn Interv Radiol       Date:  2015 Jul-Aug       Impact factor: 2.630

3.  Cellular Fibroma of Ovary Coexisting with Proliferative Endometrium Post Menopause: A Rare Presentation.

Authors:  Vandana Mohapatra; Susama Patra; Mamita Nayak; Radhamohan Gharei; Nibedita Sahoo
Journal:  J Clin Diagn Res       Date:  2017-07-01

4.  Ovarian fibroma with torsion in a young female.

Authors:  Sonal Saran; Abhay Pratap Singh; Tanvi Khanna
Journal:  Ann Afr Med       Date:  2019 Oct-Dec

5.  Ultrasound features of immature ovarian teratomas: Case series and review of literature.

Authors:  S Abdullahi Idle; K Hayes; J A Ross
Journal:  Ultrasound       Date:  2020-02-11

6.  Large twisted ovarian fibroma in menopausal women: a case report.

Authors:  Majdouline Boujoual; Ihsan Hakimi; Jaouad Kouach; Mohamed Oukabli; Driss Rahali Moussaoui; Mohammed Dehayni
Journal:  Pan Afr Med J       Date:  2015-04-06

Review 7.  The characteristic ultrasound features of specific types of ovarian pathology (review).

Authors:  Ahmad Sayasneh; Christine Ekechi; Laura Ferrara; Jeroen Kaijser; Catriona Stalder; Shyamaly Sur; Dirk Timmerman; Tom Bourne
Journal:  Int J Oncol       Date:  2014-11-18       Impact factor: 5.650

8.  Ovarian thecoma-fibroma groups: clinical and sonographic features with pathological comparison.

Authors:  Hui Chen; Yan Liu; Li-Fei Shen; Mei-Jiao Jiang; Zhi-Fang Yang; Guo-Ping Fang
Journal:  J Ovarian Res       Date:  2016-11-22       Impact factor: 4.234

9.  Value of diffusion-weighted imaging combined with conventional magnetic resonance imaging in the diagnosis of thecomas/fibrothecomas and their differential diagnosis with malignant pelvic solid tumors.

Authors:  Bing Yin; Wenhua Li; Yanfen Cui; Caiting Chu; Ming Ding; Jian Chen; Ping Zhang; Xiangru Wu
Journal:  World J Surg Oncol       Date:  2016-01-08       Impact factor: 2.754

  9 in total

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