O O Babatunde1, J J Forsyth. 1. School of Psychology, Sport and Exercise, Staffordshire University, Stoke on Trent, UK. o.babatunde@staffs.ac.uk
Abstract
UNLABELLED: The utility of Quantitative Ultrasound (QUS) for assessing and monitoring changes in bone health due to exercise is limited for lack of adequate research evidence. Restrictions to bone density testing and the enduring debate over repeat dual energy absorptiometry testing spells uncertainty over clinical and non-clinical evaluation of exercise for prevention of osteoporosis. This study, via systematic review and meta-analysis, aimed to paint a portrait of current evidence regarding QUS' application to monitoring bone's adaptive response to exercise interventions. METHODS: Structured and comprehensive search of databases was undertaken along with hand-searching of key journals and reference lists to locate relevant studies published up to December 2011. Twelve articles met predetermined inclusion criteria. The effect of exercise interventions for improving bone health, as measured by QUS of the calcaneum, was examined across the age spectrum. Study outcomes for analysis: absolute (dB/MHz) or relative change (%) in broadband ultrasound attenuation (BUA) and/or os calcis stiffness index were compared by calculating standardised mean difference (SMD) using fixed- and random-effects models. RESULTS: Quality of included trials varied from low to high on a scale of one to three. Four to 36months of exercise led to a significant improvement in calcaneum BUA (0.98 SMD, 95% CI 0.80, 1.16, overall effect Z-value=10.72, p=0.001) across the age spectrum. CONCLUSION: The meta-analysis attests to the sensitivity of QUS to exercise-induced changes in bone health across the age groups. QUS may be considered for use in exercise-based bone health interventions for preventing osteoporosis.
UNLABELLED: The utility of Quantitative Ultrasound (QUS) for assessing and monitoring changes in bone health due to exercise is limited for lack of adequate research evidence. Restrictions to bone density testing and the enduring debate over repeat dual energy absorptiometry testing spells uncertainty over clinical and non-clinical evaluation of exercise for prevention of osteoporosis. This study, via systematic review and meta-analysis, aimed to paint a portrait of current evidence regarding QUS' application to monitoring bone's adaptive response to exercise interventions. METHODS: Structured and comprehensive search of databases was undertaken along with hand-searching of key journals and reference lists to locate relevant studies published up to December 2011. Twelve articles met predetermined inclusion criteria. The effect of exercise interventions for improving bone health, as measured by QUS of the calcaneum, was examined across the age spectrum. Study outcomes for analysis: absolute (dB/MHz) or relative change (%) in broadband ultrasound attenuation (BUA) and/or os calcis stiffness index were compared by calculating standardised mean difference (SMD) using fixed- and random-effects models. RESULTS: Quality of included trials varied from low to high on a scale of one to three. Four to 36months of exercise led to a significant improvement in calcaneum BUA (0.98 SMD, 95% CI 0.80, 1.16, overall effect Z-value=10.72, p=0.001) across the age spectrum. CONCLUSION: The meta-analysis attests to the sensitivity of QUS to exercise-induced changes in bone health across the age groups. QUS may be considered for use in exercise-based bone health interventions for preventing osteoporosis.
Authors: Vichuda Lousuebsakul-Matthews; Donna Thorpe; Raymond Knutsen; W Larry Beeson; Gary E Fraser; Synnove F Knutsen Journal: J Sci Res Rep Date: 2015-04-30
Authors: Beatriz Lara; Juan José Salinero; Jorge Gutiérrez; Francisco Areces; Javier Abián-Vicén; Diana Ruiz-Vicente; César Gallo-Salazar; Fernando Jiménez; Juan Del Coso Journal: Eur J Appl Physiol Date: 2015-10-31 Impact factor: 3.078
Authors: Mohamed S Zulfarina; Razinah Sharif; Syed-Badrul Syarifah-Noratiqah; Ahmad M Sharkawi; Zaris-Sm Aqilah-Sm; Sabarul-Afian Mokhtar; Shuid A Nazrun; Isa Naina-Mohamed Journal: PLoS One Date: 2018-08-14 Impact factor: 3.240