Literature DB >> 23269338

Leydig cell tumour: enucleation as a therapeutic choice in a case with atypical symptoms.

Miriam García1, Teresa Dargallo, María Palacios, J Carames, Javier Gómez, Felipe Sacristán, Diego Vela.   

Abstract

OBJECTIVE: Testicular tumours are rare in paediatric patients, accounting for only 1% of tumours in boys. Leydig cell tumours are the most common gonadal stromal tumours. Since these tumours are functionally active, secreting testosterone, they characteristically produce isosexual pseudoprecocious puberty (IPP), the customary therapeutic choice being radical orchiectomy. Nowadays, considering that Leydig cell tumour in boys are invariably benign, some authors suggest a more conservative choice of therapy.
METHODS: This article presents the case of a patient with a cytological and immunohistochemical diagnosis of Leydig cell tumour with no clinical symptoms of IPP. The treatment carried out was enucleation of the tumour through a transcrotal access with subsequent follow-up monitoring.
RESULTS: After 2 years of follow up the patient remains free of symptoms and shows a degree of sexual development corresponding to his age.
CONCLUSIONS: We consider enucleation of the tumour to be a safe and effective therapy as an alternative to radical orchiectomy.

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Year:  2012        PMID: 23269338

Source DB:  PubMed          Journal:  Arch Esp Urol        ISSN: 0004-0614            Impact factor:   0.436


  2 in total

1.  Leydig cell tumors of the testis: a case report.

Authors:  Ancuta Augustina Gheorghisan-Galateanu
Journal:  BMC Res Notes       Date:  2014-09-18

Review 2.  Anabolic androgenic steroids and carcinogenicity focusing on Leydig cell: a literature review.

Authors:  Monica Salerno; Orazio Cascio; Giuseppe Bertozzi; Francesco Sessa; Antonietta Messina; Vincenzo Monda; Luigi Cipolloni; Antonio Biondi; Aurora Daniele; Cristoforo Pomara
Journal:  Oncotarget       Date:  2018-04-10
  2 in total

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