Imaging of Ménière's disease by subtraction of MR cisternography from positive perilymph image.

To visualize endolymph, perilymph, and bone separately in a single image after intravenous injection of single-dose gadodiamide, we generated a HYDROPS2 image (subtraction of MR cisternography from heavily T(2)-weighted 3-dimensional fluid-attenuated inversion recovery image) in 12 patients with suspected Ménière's disease. The contrast-to-noise ratio of endo- and perilymph did not differ significantly between the HYDROPS2 and previously reported HYDROPS (hybrid of reversed image of positive endolymph signal and native image of positive perilymph Signal) images, and scan time was 40% shorter for the HYDROPS2 than HYDROPS.