Amlodipine-induced gingival enlargement--a clinical report.

Gingival enlargement is a known side effect of calcium channel blockers--especially the dihydropyridine group. It is a serious concern for both the patient and the clinician due to its unesthetic appearance and formation of new niches for periodontopathogenic bacteria. Among the calcium channel blockers, gingival enlargement has most frequently been described as a side effect following administration of nifedipine. The incidence with amlodipine is much lower; however, there have been few reports showing the association of this drug with gingival enlargement. This case report aims to make dentists aware of the adverse effects of amlodipine, as well offers a brief review of its effects on the gingiva and the management of enlargement.