Asako Yamamoto1, Hiroshi Oba, Shigeru Furui. 1. Department of Radiology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashiku, Tokyo 173-8605, Japan. asakonemurinomori@yahoo.co.jp
Abstract
PURPOSE: To elucidate the influence of age and sex on the signal intensity (SI) of the posterior lobe of the pituitary gland (PPG) on T1-weighted images (T1WI) from 3 T MRI. MATERIALS AND METHODS: Sagittal T1WI acquired from three-dimensional fast spoiled gradient recalled acquisition in the steady state in 1,634 subjects without conditions affecting antidiuretic hormone were evaluated retrospectively. The presence or absence of a bright signal in the PPG was assessed qualitatively. The SI ratio of the PPG to the pons (SIR) was obtained from quantitative measurements. We statistically analyzed these data, creating 14 subject groups categorized according to age and sex, and applied a Poisson generalized linear model to the SIR data. RESULTS: The characteristic bright signal was absent in 47 subjects (2.8 %), with no significant difference in incidence among the groups. The SIR was inversely related to age in both males (r > 0.7) and females (r > 0.9), and was significantly higher in females in the third to the eighth decades (p < 0.05). Analysis of the whole SIR dataset using a generalized linear model showed that the estimated SIR decreased by 1.7 % per decade and is higher in females. CONCLUSION: Age and sex influence the SI of the PPG on T1WI. These findings may aid the recognition of PPG signal abnormalities on T1WI.
PURPOSE: To elucidate the influence of age and sex on the signal intensity (SI) of the posterior lobe of the pituitary gland (PPG) on T1-weighted images (T1WI) from 3 T MRI. MATERIALS AND METHODS: Sagittal T1WI acquired from three-dimensional fast spoiled gradient recalled acquisition in the steady state in 1,634 subjects without conditions affecting antidiuretic hormone were evaluated retrospectively. The presence or absence of a bright signal in the PPG was assessed qualitatively. The SI ratio of the PPG to the pons (SIR) was obtained from quantitative measurements. We statistically analyzed these data, creating 14 subject groups categorized according to age and sex, and applied a Poisson generalized linear model to the SIR data. RESULTS: The characteristic bright signal was absent in 47 subjects (2.8 %), with no significant difference in incidence among the groups. The SIR was inversely related to age in both males (r > 0.7) and females (r > 0.9), and was significantly higher in females in the third to the eighth decades (p < 0.05). Analysis of the whole SIR dataset using a generalized linear model showed that the estimated SIR decreased by 1.7 % per decade and is higher in females. CONCLUSION: Age and sex influence the SI of the PPG on T1WI. These findings may aid the recognition of PPG signal abnormalities on T1WI.
Authors: I Fujisawa; R Asato; M Kawata; Y Sano; K Nakao; T Yamada; H Imura; Y Naito; K Hoshino; S Noma Journal: J Comput Assist Tomogr Date: 1989 May-Jun Impact factor: 1.826
Authors: Tarek Sharshar; Robert Carlier; Anne Blanchard; Antoine Feydy; Françoise Gray; Michel Paillard; Jean-Claude Raphael; Philippe Gajdos; Djillaii Annane Journal: Crit Care Med Date: 2002-03 Impact factor: 7.598