Literature DB >> 23266578

Comparison of two molecular assays with conventional blood culture for diagnosis of sepsis.

Eva Leitner1, Harald H Kessler, Walter Spindelboeck, Martin Hoenigl, Csilla Putz-Bankuti, Vanessa Stadlbauer-Köllner, Robert Krause, Andrea J Grisold, Gebhard Feierl, Rudolf E Stauber.   

Abstract

In this small study, the LightCycler® SeptiFast, and the SepsiTest™ were compared with blood culture. The SeptiFast showed a higher sensitivity (42.9%) and specificity (88.2%) when compared to blood culture than the SepsiTest™ (28.6 and 85.3%). The SeptiFast provides more species specific results, although the identification panel is smaller.
Copyright © 2012 Elsevier B.V. All rights reserved.

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Year:  2012        PMID： 23266578     DOI： 10.1016/j.mimet.2012.12.012

Source DB:  PubMed          Journal:  J Microbiol Methods        ISSN： 0167-7012            Impact factor:   2.363


  14 in total

1.  Non-culture-based methods to diagnose bloodstream infection: Does it work?

Authors:  Miha Skvarc; David Stubljar; Petra Rogina; Achim J Kaasch
Journal:  Eur J Microbiol Immunol (Bp)       Date:  2013-06-05

Review 2.  Accuracy of LightCycler(®) SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review and meta-analysis.

Authors:  Paul Dark; Bronagh Blackwood; Simon Gates; Danny McAuley; Gavin D Perkins; Ronan McMullan; Claire Wilson; Daniel Graham; Kate Timms; Geoffrey Warhurst
Journal:  Intensive Care Med       Date:  2014-11-22       Impact factor: 17.440

3.  Molecular diagnosis of sepsis: New aspects and recent developments.

Authors:  O Liesenfeld; L Lehman; K-P Hunfeld; G Kost
Journal:  Eur J Microbiol Immunol (Bp)       Date:  2014-03-14

Review 4.  Emerging Technologies for Molecular Diagnosis of Sepsis.

Authors:  Mridu Sinha; Julietta Jupe; Hannah Mack; Todd P Coleman; Shelley M Lawrence; Stephanie I Fraley
Journal:  Clin Microbiol Rev       Date:  2018-02-28       Impact factor: 26.132

Review 5.  Commercial multiplex technologies for the microbiological diagnosis of sepsis.

Authors:  Evan E Lebovitz; Peter D Burbelo
Journal:  Mol Diagn Ther       Date:  2013-08       Impact factor: 4.074

6.  Rapid diagnosis of bloodstream infections with PCR followed by mass spectrometry.

Authors:  Elena Jordana-Lluch; Heather E Carolan; Montserrat Giménez; Rangarajan Sampath; David J Ecker; M Dolores Quesada; Josep M Mòdol; Fernando Arméstar; Lawrence B Blyn; Lendell L Cummins; Vicente Ausina; Elisa Martró
Journal:  PLoS One       Date:  2013-04-23       Impact factor: 3.240

7.  Evaluation of a Commercial Multiplex PCR Assay for Detection of Pathogen DNA in Blood from Patients with Suspected Sepsis.

Authors:  Ingrid Ziegler; Anna Fagerström; Kristoffer Strålin; Paula Mölling
Journal:  PLoS One       Date:  2016-12-20       Impact factor: 3.240

Review 8.  Revolutionising bacteriology to improve treatment outcomes and antibiotic stewardship.

Authors:  David M Livermore; John Wain
Journal:  Infect Chemother       Date:  2013-03-29

Review 9.  Improving the diagnosis of bloodstream infections: PCR coupled with mass spectrometry.

Authors:  Elena Jordana-Lluch; Montserrat Giménez; M Dolores Quesada; Vicente Ausina; Elisa Martró
Journal:  Biomed Res Int       Date:  2014-04-09       Impact factor: 3.411

Review 10.  Application of Culture-Independent Rapid Diagnostic Tests in the Management of Invasive Candidiasis and Cryptococcosis.

Authors:  Michael A Pfaller
Journal:  J Fungi (Basel)       Date:  2015-08-31
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