Literature DB >> 23265879

Synthesis and evaluation of novel sulfenamides as novel anti Methicillin-resistant Staphylococcus aureus agents.

Jian-Li Shang1, Hui Guo, Zai-Shun Li, Biao Ren, Zheng-Ming Li, Huan-qin Dai, Li-Xin Zhang, Jian-Guo Wang.   

Abstract

A total of 29 novel sulfenamide compounds were synthesized, spectroscopically characterized and evaluated in vitro for antimicrobial activity against various infectious pathogens. Compounds 1b and 2c exhibited potent inhibition against clinical Methicillin-resistant Staphylococcus aureus (MRSA) strains with minimum inhibitory concentration (MIC) values of 1.56 μg/mL.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID: 23265879     DOI: 10.1016/j.bmcl.2012.11.103

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

1.  Proline-based phosphoramidite reagents for the reductive ligation of S-nitrosothiols.

Authors:  Chung-Min Park; Tyler D Biggs; Ming Xian
Journal:  J Antibiot (Tokyo)       Date:  2016-01-13       Impact factor: 2.649

  1 in total

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