Literature DB >> 23265582

Endovascular repair of ruptured infrarenal abdominal aortic aneurysm is associated with lower 30-day mortality and better 5-year survival rates than open surgical repair.

Manish Mehta1, John Byrne, R Clement Darling, Philip S K Paty, Sean P Roddy, Paul B Kreienberg, John B Taggert, Paul Feustel.   

Abstract

OBJECTIVE: Endovascular aneurysm repair (EVAR) decreases 30-day mortality for patients with ruptured abdominal aortic aneurysms (r-AAAs) compared with open surgical repair (OSR). However, which patients benefit or whether there is any long-term survival advantage is uncertain.
METHODS: From 2002 to 2011, 283 patients with r-AAA underwent EVAR (n = 120 [42.4%]) or OSR (n = 163 [57.6%]) at Albany Medical Center. All data were collected prospectively. Patients were analyzed on an intention-to-treat basis, and outcomes were evaluated by a logistic regression multivariable model. Kaplan-Meier analysis was used to compare long-term survival.
RESULTS: The EVAR patients had a significantly lower 30-day mortality than did the OSR patients (29/120 [24.2%] vs 72/163 [44.2%]; P < .005) and better cumulative 5-year survival (37% vs 26%; P < .005). Men benefited more from EVAR (mortality: 20.9% for EVAR vs 44.3% for OSR; P < .001) than did women (mortality: 32.4% vs 43.9%; P = .39). Age ≥80 years was a significant predictor of death for EVAR (odds ratio [OR], 1.07; P = .003) but not for OSR (OR, 1.04; P = .056). Preexisting hypertension was a significant predictor of survival for both EVAR (OR, 0.17; P < .001) and OSR (OR, 0.48; P = .021). Almost one fourth of EVAR patients (21/91 [23.1%]) required secondary interventions. Survival advantage was maintained for EVAR patients to 5 years.
CONCLUSIONS: For r-AAA, EVAR reduces the 30-day mortality and improves long-term survival up to 5 years. However, whereas open survivors require few graft-related interventions, up to 23% of EVAR patients will require reintervention for endoleaks or graft migration. Close follow-up of all EVAR survivors is mandatory.
Copyright © 2013 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.

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Year:  2012        PMID: 23265582     DOI: 10.1016/j.jvs.2012.09.003

Source DB:  PubMed          Journal:  J Vasc Surg        ISSN: 0741-5214            Impact factor:   4.268


  22 in total

1.  Endovascular repair first for ruptured abdominal aortic aneurysms.

Authors:  Justin Galovich; Carlos Donayre; John Lin; Irwin Walot; Rodney A White
Journal:  Tex Heart Inst J       Date:  2013

2.  Significant regional variation exists in morbidity and mortality after repair of abdominal aortic aneurysm.

Authors:  Sara L Zettervall; Peter A Soden; Dominique B Buck; Jack L Cronenwett; Phillip P Goodney; Mohammad H Eslami; Jason T Lee; Marc L Schermerhorn
Journal:  J Vasc Surg       Date:  2016-11-23       Impact factor: 4.268

3.  Influencing factors of immediate angiographic results in intracranial aneurysms patients after endovascular treatment.

Authors:  Jia-Xiang Chen; Ling-Feng Lai; Kuang Zheng; Guo-Xiong Li; Xu-Ying He; Liang-Ping Li; Chuan-Zhi Duan
Journal:  J Neurol       Date:  2015-06-24       Impact factor: 4.849

4.  Clinical outcomes of infrarenal abdominal aortic aneurysms that underwent endovascular repair in a district general hospital.

Authors:  Chih-Hsien Lee; Chien-Jung Chang; Jau-Kang Huang; Ten-Fang Yang
Journal:  J Thorac Dis       Date:  2016-07       Impact factor: 2.895

Review 5.  Emergent Endovascular Stent Grafts for Ruptured Aortic Aneurysms.

Authors:  Jennifer P Montgomery; Kenneth J Kolbeck; John A Kaufman
Journal:  Semin Intervent Radiol       Date:  2015-09       Impact factor: 1.513

6.  Regional variation exists in patient selection and treatment of abdominal aortic aneurysms.

Authors:  Sara L Zettervall; Dominique B Buck; Peter A Soden; Jack L Cronenwett; Phillip P Goodney; Mohammad H Eslami; Jason T Lee; Marc L Schermerhorn
Journal:  J Vasc Surg       Date:  2016-04-08       Impact factor: 4.268

7.  Open surgery (OS) versus endovascular aneurysm repair (EVAR) for hemodynamically stable and unstable ruptured abdominal aortic aneurysm (rAAA).

Authors:  Simeng Zhang; Jiaxuan Feng; Haiyan Li; Yongxue Zhang; Qingsheng Lu; Zaiping Jing
Journal:  Heart Vessels       Date:  2015-09-03       Impact factor: 2.037

8.  Predictors of renal dysfunction after endovascular and open repair of abdominal aortic aneurysms.

Authors:  Sara L Zettervall; Klaas H J Ultee; Peter A Soden; Sarah E Deery; Katie E Shean; Alexander B Pothof; Mark Wyers; Marc L Schermerhorn
Journal:  J Vasc Surg       Date:  2016-09-26       Impact factor: 4.268

9.  Recent risk factors for open surgical mortality in patients with ruptured abdominal aortic aneurysm.

Authors:  Kenichiro Uchida; Akinori Io; Sho Akita; Hisaaki Munakata; Makoto Hibino; Kei Fujii; Wataru Kato; Yoshimasa Sakai; Kazuyoshi Tajima; Yasumitsu Mizobata
Journal:  Acute Med Surg       Date:  2014-05-19

10.  Long-term safety and efficacy of endovascular abdominal aortic aneurysm repair.

Authors:  Brandon W Propper; Christopher J Abularrage
Journal:  Vasc Health Risk Manag       Date:  2013-04-03
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