Literature DB >> 23265578

Management of cerebrospinal fluid leak during endoscopic pituitary surgery.

Mustafa Berker1, Kamran Aghayev, Taşkın Yücel, Derya Burcu Hazer, Metin Onerci.   

Abstract

OBJECTIVE: Dural opening and closures are major steps in endoscopic pituitary surgery. Restoring the normal anatomy at the end of the procedure creates a natural barrier between the intrasellar compartment and the sinonasal cavity.
METHODS: In this study, we present a relatively simple dural opening and closure technique for endoscopic pituitary surgery. This technique provides a better alternative to the use of a more complex nasoseptal flap or the multilevel closure with artificial materials as it restores the normal anatomy after the tumor removal and provides a better physiological barrier between the sinonasal cavity and the intrasellar compartment. Incision is performed in circular or horseshoe fashion leaving a small peduncle, and then the dura is reflected.
RESULTS: Of the 733 endoscopic transsphenoidal procedures in 667 patients conducted between January 2006 and May 2012, we used this described technique in 50 cases (7.4%). In these 50 cases with dural flap, there was no postoperative CSF leakage. Intraoperative CSF leakage was observed in 135 (20.2%) of the 667 patients. In 15 (11.1%) of these 135 patients we used the dural flap technique accompanied with fat and/or fascia lata support. There was no postoperative leakage in these patients. In the remaining 120 (89.9%) patients who had intraoperative CSF leakage, we used fat and/or fascia lata for the reconstruction of the sella floor. But we observed postoperative CSF leakage in 12 (10%) of the 120 patients without the dural flap which were reoperated.
CONCLUSION: The dural flap technique we employ has several advantages. First of all, it allows optimal physiological reconstruction after the surgery. Secondly, the bridge between the flap and the main dura helps maintain the vascular supply, which in turn can radically shorten the healing time. Thirdly, this technique is obviously a better alternative to the time consuming and expensive multilevel closures with tissue sealants and artificial grafts.
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

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Mesh:

Year:  2012        PMID: 23265578     DOI: 10.1016/j.anl.2012.11.006

Source DB:  PubMed          Journal:  Auris Nasus Larynx        ISSN: 0385-8146            Impact factor:   1.863


  6 in total

1.  A novel graft material for preventing cerebrospinal fluid leakage in skull base reconstruction: technical note of perifascial areolar tissue.

Authors:  Nakamasa Hayashi; Koichi Mitsuya; Katsuya Gorai; Keita Inoue; Ichiro Ito; Masahiro Nakagawa; Yoko Nakasu
Journal:  J Neurol Surg B Skull Base       Date:  2014-08-11

2.  Heterogeneity in Outcome Reporting in Endoscopic Endonasal Skull Base Reconstruction: A Systematic Review.

Authors:  Christina Dorismond; Griffin D Santarelli; Brian D Thorp; Adam J Kimple; Charles S Ebert; Adam M Zanation
Journal:  J Neurol Surg B Skull Base       Date:  2020-08-07

3.  Sellar Reconstruction and Rates of Delayed Cerebrospinal Fluid Leak after Endoscopic Pituitary Surgery.

Authors:  Chris Sanders-Taylor; Amjad Anaizi; Jennifer Kosty; Lee A Zimmer; Phillip V Theodosopoulos
Journal:  J Neurol Surg B Skull Base       Date:  2015-03-02

4.  Endoscopic Endonasal Transsphenoidal Approach for Apoplectic Pituitary Tumor: Surgical Outcomes and Complications in 45 Patients.

Authors:  Rucai Zhan; Xueen Li; Xingang Li
Journal:  J Neurol Surg B Skull Base       Date:  2015-08-20

5.  Acute Hemorrhagic Apoplectic Pituitary Adenoma: Endoscopic Management, Surgical Outcomes, and Complications.

Authors:  Rucai Zhan; Yanxin Zhao; Timothy M Wiebe; Xingang Li
Journal:  J Craniofac Surg       Date:  2015-09       Impact factor: 1.046

6.  Skull base repair following endonasal pituitary and skull base tumour resection: a systematic review.

Authors:  Danyal Z Khan; Ahmad M S Ali; Chan Hee Koh; Neil L Dorward; Joan Grieve; Hugo Layard Horsfall; William Muirhead; Thomas Santarius; Wouter R Van Furth; Amir H Zamanipoor Najafabadi; Hani J Marcus
Journal:  Pituitary       Date:  2021-05-10       Impact factor: 4.107

  6 in total

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