Anda Botoseneanu1, Jersey Liang. 1. Department of Internal Medicine/Geriatrics, Yale University, New Haven, CT 06510, USA. andabm@umich.edu
Abstract
OBJECTIVE: To evaluate latent heterogeneity in long-term trajectories of body weight in older adults. METHODS: We analyzed 14-year longitudinal data on 10,314 older adults from the Health and Retirement Study. Semiparametric mixture models identified latent subgroups of similar trajectories of body mass index (BMI). RESULTS: Five distinct trajectory subgroups emerged: normal starting-BMI with accelerated increase over time (trajectory #1), overweight and increasing (trajectory #2), borderline-obese and increasing (trajectory #3), obese and increasing (trajectory #4), and morbidly obese with decelerating gain (trajectory #5). Blacks and Hispanics had greater risk of membership in ascending high-BMI trajectory groups. Females had approximately half the risk of following overweight and obese increasing BMI trajectories compared with males. DISCUSSION: Distinct latent subgroups of BMI trajectories and significant racial/ethnic and gender trajectory heterogeneity exist in the older adult population. The propensity of men and minorities to experience high-risk BMI trajectories may exacerbate existing disparities in morbidity/ mortality in older age.
OBJECTIVE: To evaluate latent heterogeneity in long-term trajectories of body weight in older adults. METHODS: We analyzed 14-year longitudinal data on 10,314 older adults from the Health and Retirement Study. Semiparametric mixture models identified latent subgroups of similar trajectories of body mass index (BMI). RESULTS: Five distinct trajectory subgroups emerged: normal starting-BMI with accelerated increase over time (trajectory #1), overweight and increasing (trajectory #2), borderline-obese and increasing (trajectory #3), obese and increasing (trajectory #4), and morbidly obese with decelerating gain (trajectory #5). Blacks and Hispanics had greater risk of membership in ascending high-BMI trajectory groups. Females had approximately half the risk of following overweight and obese increasing BMI trajectories compared with males. DISCUSSION: Distinct latent subgroups of BMI trajectories and significant racial/ethnic and gender trajectory heterogeneity exist in the older adult population. The propensity of men and minorities to experience high-risk BMI trajectories may exacerbate existing disparities in morbidity/ mortality in older age.
Authors: Bethany B Barone; Jeanne M Clark; Nae-Yuh Wang; Lucy A Meoni; Michael J Klag; Frederick L Brancati Journal: Obesity (Silver Spring) Date: 2006-05 Impact factor: 5.002
Authors: Cynthia L Ogden; Margaret D Carroll; Lester R Curtin; Margaret A McDowell; Carolyn J Tabak; Katherine M Flegal Journal: JAMA Date: 2006-04-05 Impact factor: 56.272
Authors: Hiroshi Murayama; Jersey Liang; Joan M Bennett; Benjamin A Shaw; Anda Botoseneanu; Erika Kobayashi; Taro Fukaya; Shoji Shinkai Journal: Am J Epidemiol Date: 2015-09-12 Impact factor: 4.897
Authors: Melina Arnold; Heinz Freisling; Rachael Stolzenberg-Solomon; Frank Kee; Mark George O'Doherty; José Manuel Ordóñez-Mena; Tom Wilsgaard; Anne Maria May; Hendrik Bas Bueno-de-Mesquita; Anne Tjønneland; Philippos Orfanos; Antonia Trichopoulou; Paolo Boffetta; Freddie Bray; Mazda Jenab; Isabelle Soerjomataram Journal: Eur J Epidemiol Date: 2016-06-14 Impact factor: 8.082
Authors: Parnian Parvin; Parisa Amiri; Mohammad Masih Mansouri-Tehrani; Leila Cheraghi; Amirali Zareie Shab-Khaneh; Fereidoun Azizi Journal: Qual Life Res Date: 2021-11-20 Impact factor: 4.147
Authors: Cynthia A Thomson; David O Garcia; Betsy C Wertheim; Melanie D Hingle; Jennifer W Bea; Oleg Zaslavsky; Graciela Caire-Juvera; Thomas Rohan; Mara Z Vitolins; Patricia A Thompson; Cora E Lewis Journal: Obesity (Silver Spring) Date: 2016-03-15 Impact factor: 5.002
Authors: Sari Stenholm; Jussi Vahtera; Ichiro Kawachi; Jaana Pentti; Jaana I Halonen; Hugo Westerlund; Fahad Razak; S V Subramanian; Mika Kivimäki Journal: Epidemiology Date: 2015-03 Impact factor: 4.822
Authors: Penny Gordon-Larsen; Elizabeth Koehler; Annie Green Howard; Lauren Paynter; Amanda L Thompson; Linda S Adair; Elizabeth J Mayer-Davis; Bing Zhang; Barry M Popkin; Amy H Herring Journal: Diabetologia Date: 2014-06-03 Impact factor: 10.122