OBJECTIVE: To identify perinatal and neonatal risk factors associated with developmental coordination disorder (DCD) in very low birthweight children (VLBW: <1250 g). DESIGN: Retrospective design with prospectively collected cohort. SETTING: Neonatal Follow-Up Program, Vancouver, Canada. PATIENTS: 157 VLBW children assessed at 4-5 years who were free of cerebral palsy or major neurological impairment and had full-scale IQ >70. MAIN OUTCOME MEASURE: Movement assessment battery for children (MABC). RESULTS: Using ≤15th percentile on the MABC as the cut-off, 42% of our cohort developed DCD. Perinatal variables significantly associated with DCD were male sex, lower gestational age and lower birth weight, but only male sex and low birth weight independently predicted DCD, accounting for 20% of the variance in MABC scores. Compared with children without motor impairment, children with DCD had greater postnatal steroid exposure, longer duration of ventilation, more days on oxygen and significant retinopathy of prematurity, but only postnatal steroid exposure was significant, accounting for an additional 3% of the variance in MABC scores. Boys performed more poorly than girls on all subtests of the MABC. CONCLUSIONS: Male sex and low birth weight were significant predictors of DCD, suggesting that these infants should be followed for detection of this common, but under-recognised disorder. Future research aimed at identifying neural underpinnings of DCD and possible antecedents to the disorder is warranted.
OBJECTIVE: To identify perinatal and neonatal risk factors associated with developmental coordination disorder (DCD) in very low birthweight children (VLBW: <1250 g). DESIGN: Retrospective design with prospectively collected cohort. SETTING: Neonatal Follow-Up Program, Vancouver, Canada. PATIENTS: 157 VLBW children assessed at 4-5 years who were free of cerebral palsy or major neurological impairment and had full-scale IQ >70. MAIN OUTCOME MEASURE: Movement assessment battery for children (MABC). RESULTS: Using ≤15th percentile on the MABC as the cut-off, 42% of our cohort developed DCD. Perinatal variables significantly associated with DCD were male sex, lower gestational age and lower birth weight, but only male sex and low birth weight independently predicted DCD, accounting for 20% of the variance in MABC scores. Compared with children without motor impairment, children with DCD had greater postnatal steroid exposure, longer duration of ventilation, more days on oxygen and significant retinopathy of prematurity, but only postnatal steroid exposure was significant, accounting for an additional 3% of the variance in MABC scores. Boys performed more poorly than girls on all subtests of the MABC. CONCLUSIONS: Male sex and low birth weight were significant predictors of DCD, suggesting that these infants should be followed for detection of this common, but under-recognised disorder. Future research aimed at identifying neural underpinnings of DCD and possible antecedents to the disorder is warranted.
Authors: Rainer Blank; Anna L Barnett; John Cairney; Dido Green; Amanda Kirby; Helene Polatajko; Sara Rosenblum; Bouwien Smits-Engelsman; David Sugden; Peter Wilson; Sabine Vinçon Journal: Dev Med Child Neurol Date: 2019-01-22 Impact factor: 5.449
Authors: Dalit Cayam-Rand; Ting Guo; Ruth E Grunau; Isabel Benavente-Fernández; Anne Synnes; Vann Chau; Helen Branson; Beatrice Latal; Patrick McQuillen; Steven P Miller Journal: Neurology Date: 2019-08-29 Impact factor: 11.800
Authors: Cecil M Y Chau; Manon Ranger; Dian Sulistyoningrum; Angela M Devlin; Tim F Oberlander; Ruth E Grunau Journal: Front Behav Neurosci Date: 2014-12-02 Impact factor: 3.558
Authors: Adja J M Waelput; Meertien K Sijpkens; Jacqueline Lagendijk; Minke R C van Minde; Hein Raat; Hiske E Ernst-Smelt; Marlou L A de Kroon; Ageeth N Rosman; Jasper V Been; Loes C M Bertens; Eric A P Steegers Journal: BMC Pregnancy Childbirth Date: 2017-08-01 Impact factor: 3.007