Literature DB >> 23263551

Association of interleukin-18 and systemic lupus erythematosus.

Wang-Dong Xu1, Hai-Feng Pan, Dong-Qing Ye.   

Abstract

Interleukin-18 (IL-18), belongs to the IL-1 cytokine family, has a variety of effects on dendritic cell, T cell, natural killer cell. Previous studies have identified that IL-18 was associated with the pathogenesis of systemic lupus erythematosus (SLE), wherein elevated expression of IL-18 was found in the serum of patients, and IL-18 polymorphisms with susceptibility to SLE were reported, suggesting that IL-18 may be therapeutically relevant to SLE. In this article, we will discuss the role of IL-18 in the pathogenesis of and its therapeutic potential in SLE based on current understandings.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 23263551     DOI： 10.1007/s00296-012-2623-x

Source DB:  PubMed          Journal:  Rheumatol Int        ISSN： 0172-8172            Impact factor:   2.631


  24 in total

Review 1.  Systemic lupus erythematosus.

Authors:  George C Tsokos
Journal:  N Engl J Med       Date:  2011-12-01       Impact factor: 91.245

2.  Serum and urinary levels of IL-18 and its inhibitor IL-18BP in systemic lupus erythematosus.

Authors:  Paola Migliorini; Consuelo Anzilotti; Federico Pratesi; Paola Quattroni; Marco Bargagna; Charles A Dinarello; Diana Boraschi
Journal:  Eur Cytokine Netw       Date:  2010-12-03       Impact factor: 2.737

3.  Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation.

Authors:  Pei-Yi Tsai; Shuk-Man Ka; Jia-Ming Chang; Hsiang-Cheng Chen; Hao-Ai Shui; Chen-Yun Li; Kuo-Feng Hua; Wen-Liang Chang; Jiann-Jyh Huang; Sung-Sen Yang; Ann Chen
Journal:  Free Radic Biol Med       Date:  2011-05-23       Impact factor: 7.376

4.  Phenotype and function of natural killer cells in systemic lupus erythematosus: excess interferon-γ production in patients with active disease.

Authors:  Baptiste Hervier; Vivien Beziat; Julien Haroche; Alexis Mathian; Pierre Lebon; Pascale Ghillani-Dalbin; Lucile Musset; Patrice Debré; Zahir Amoura; Vincent Vieillard
Journal:  Arthritis Rheum       Date:  2011-06

5.  Antroquinonol differentially modulates T cell activity and reduces interleukin-18 production, but enhances Nrf2 activation, in murine accelerated severe lupus nephritis.

Authors:  Pei-Yi Tsai; Shuk-Man Ka; Jia-Ming Chang; Jenn-Haung Lai; Ming-Shen Dai; Huei-Lin Jheng; Mao-Tien Kuo; Peini Chen; Ann Chen
Journal:  Arthritis Rheum       Date:  2012-01

6.  Association of interleukin-18 promoter polymorphisms with WHO pathological classes and serum IL-18 levels in Chinese patients with lupus nephritis.

Authors:  D Y Chen; C W Hsieh; K S Chen; Y M Chen; F J Lin; J L Lan
Journal:  Lupus       Date:  2009-01       Impact factor: 2.911

7.  IL-18 105 A>C polymorphism contributes to renal manifestations in patients with SLE.

Authors:  Teresa Warchoł; Margarita Lianeri; Mariusz Wudarski; Jan K Lacki; Paweł Piotr Jagodziński
Journal:  Rheumatol Int       Date:  2009-12       Impact factor: 2.631

8.  The human interleukin 18 gene IL18 maps to 11q22.2-q22.3, closely linked to the DRD2 gene locus and distinct from mapped IDDM loci.

Authors:  K F Nolan; D R Greaves; H Waldmann
Journal:  Genomics       Date:  1998-07-01       Impact factor: 5.736

9.  Disease association of the interleukin-18 promoter polymorphisms in Taiwan Chinese systemic lupus erythematosus patients.

Authors:  Y-J Lin; L Wan; C-C Lee; C-M Huang; Y Tsai; C-H Tsai; T-L Shin; K Chao; C-M Liu; J-W Xiao; F-J Tsai
Journal:  Genes Immun       Date:  2007-03-15       Impact factor: 2.676

10.  Identification of a new putative functional IL18 gene variant through an association study in systemic lupus erythematosus.

Authors:  Elena Sánchez; Rogelio J Palomino-Morales; Norberto Ortego-Centeno; Juan Jiménez-Alonso; Miguel A González-Gay; Miguel A López-Nevot; Julio Sánchez-Román; Enrique de Ramón; M Francisca González-Escribano; Bernardo A Pons-Estel; Sandra D'Alfonso; Gian Domenico Sebastiani; Marta E Alarcón-Riquelme; Javier Martín
Journal:  Hum Mol Genet       Date:  2009-07-07       Impact factor: 6.150
View more
  6 in total

1.  Elevated serum levels of interleukin-1β and interleukin-33 in patients with systemic sclerosis in Chinese population.

Authors:  Y-J Zhang; Q Zhang; G-J Yang; J-H Tao; G-C Wu; X-L Huang; Y Duan; X-P Li; D-Q Ye; J Wang
Journal:  Z Rheumatol       Date:  2018-03       Impact factor: 1.372

Review 2.  Potential roles of nucleotide-binding oligomerization domain 2 in the pathogenesis of systemic lupus erythematosus.

Authors:  Jing Li; Song Wu; Ming-Rui Wang; Ting-Ting Wang; Bai-Kun Li; Ji-Min Zhu
Journal:  Rheumatol Int       Date:  2014-03-06       Impact factor: 2.631

3.  Extremely elevated IL-18 levels may help distinguish systemic-onset juvenile idiopathic arthritis from other febrile diseases.

Authors:  Y Xia; P Cui; Q Li; F Liang; C Li; J Yang
Journal:  Braz J Med Biol Res       Date:  2017-02-16       Impact factor: 2.590

Review 4.  Programmed Cell Death Pathways in the Pathogenesis of Systemic Lupus Erythematosus.

Authors:  Fangyuan Yang; Yi He; Zeqing Zhai; Erwei Sun
Journal:  J Immunol Res       Date:  2019-12-01       Impact factor: 4.818

5.  Elevated Serum Interleukin-34 Level in Patients with Systemic Lupus Erythematosus Is Associated with Disease Activity.

Authors:  Huan Huan Xie; Hui Shen; Li Zhang; Mei Ying Cui; Li Ping Xia; Jing Lu
Journal:  Sci Rep       Date:  2018-02-22       Impact factor: 4.379

6.  Elevation of Interleukin-18 Correlates With Cardiovascular, Cerebrovascular, and Peripheral Vascular Events: A Cohort Study of Hemodialysis Patients.

Authors:  Chih-Hsiang Chang; Pei-Chun Fan; Chan-Yu Lin; Chia-Hung Yang; Yi-Ting Chen; Su-Wei Chang; Huang-Yu Yang; Chang-Chyi Jenq; Cheng-Chieh Hung; Chih-Wei Yang; Yung-Chang Chen
Journal:  Medicine (Baltimore)       Date:  2015-10       Impact factor: 1.817
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.