Literature DB >> 23262805

Developing a national 'low risk' febrile neutropenia framework for use in children and young people's cancer care.

F Gibson1, J Chisholm, E Blandford, P Donachie, J Hartley, S Lane, K Selwood, R Skinner, R Phillips.   

Abstract

PURPOSE: A Delphi study was undertaken to develop a framework guidance that would rationalise and standardise the care of children with febrile neutropenia (FNP) across the UK.
METHODS: A mailed Delphi survey was undertaken with health professionals working in children's cancer units. The survey employed two rounds of feedback on 22 practice statements drawn from a systematic review of clinical evidence. Consensus was assumed for any statement where 80+ % of respondents indicated that they "agreed" or "strongly agreed".
RESULTS: Consensus was reached on 21 of the 22 practice statements in round 1 that were categorised into six areas: definition of fever and neutropenia, initial management and choice of antibiotic, defining low-risk patients, strategy in low-risk patients and alternative approaches. Consensus could not be reached on whether patients needed to be afebrile to be suitable for discharge and the required length of outpatient antibiotic treatment.
CONCLUSIONS: A Delphi survey allowed the successful development of a national framework for identification and management of children with FNP. The use of an existing well-functioning professional network was key in this project's success.

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Year:  2012        PMID: 23262805     DOI: 10.1007/s00520-012-1653-y

Source DB:  PubMed          Journal:  Support Care Cancer        ISSN: 0941-4355            Impact factor:   3.603


  34 in total

1.  Successes and failures in the implementation of evidence-based guidelines for clinical practice.

Authors:  R Grol
Journal:  Med Care       Date:  2001-08       Impact factor: 2.983

2.  Oral ciprofloxacin vs. intravenous ceftriaxone administered in an outpatient setting for fever and neutropenia in low-risk pediatric oncology patients: randomized prospective trial.

Authors:  A S Petrilli; L S Dantas; M C Campos; C Tanaka; V C Ginani; A Seber
Journal:  Med Pediatr Oncol       Date:  2000-02

3.  Development of a clinical guideline for palliative sedation therapy using the Delphi method.

Authors:  Tatsuya Morita; Seiji Bito; Yukie Kurihara; Yosuke Uchitomi
Journal:  J Palliat Med       Date:  2005-08       Impact factor: 2.947

Review 4.  The Delphi technique: a critique.

Authors:  C M Goodman
Journal:  J Adv Nurs       Date:  1987-11       Impact factor: 3.187

5.  Randomized placebo-controlled trial of oral antibiotics in pediatric oncology patients at low-risk with fever and neutropenia.

Authors:  R J Klaassen; U Allen; J J Doyle
Journal:  J Pediatr Hematol Oncol       Date:  2000 Sep-Oct       Impact factor: 1.289

6.  Extended-interval aminoglycoside administration for children: a meta-analysis.

Authors:  Despina G Contopoulos-Ioannidis; Nikos D Giotis; Dimitra V Baliatsa; John P A Ioannidis
Journal:  Pediatrics       Date:  2004-07       Impact factor: 7.124

7.  Applying the Delphi process to palliative care tool development: lessons learned.

Authors:  Patricia D Biondo; Cheryl L Nekolaichuk; Carla Stiles; Robin Fainsinger; Neil A Hagen
Journal:  Support Care Cancer       Date:  2007-10-30       Impact factor: 3.603

8.  Predicting bacteremia in children with fever and chemotherapy-induced neutropenia.

Authors:  Roland A Ammann; Andreas Hirt; Annette Ridolfi Lüthy; Christoph Aebi
Journal:  Pediatr Infect Dis J       Date:  2004-01       Impact factor: 2.129

9.  The identification of febrile, neutropenic children with neoplastic disease at low risk for bacteremia and complications of sepsis.

Authors:  K G Lucas; A E Brown; D Armstrong; D Chapman; G Heller
Journal:  Cancer       Date:  1996-02-15       Impact factor: 6.860

10.  How can we improve guideline use? A conceptual framework of implementability.

Authors:  Anna R Gagliardi; Melissa C Brouwers; Valerie A Palda; Louise Lemieux-Charles; Jeremy M Grimshaw
Journal:  Implement Sci       Date:  2011-03-22       Impact factor: 7.327

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  3 in total

1.  The influence of different fever definitions on the rate of fever in neutropenia diagnosed in children with cancer.

Authors:  Roland A Ammann; Oliver Teuffel; Philipp Agyeman; Nadine Amport; Kurt Leibundgut
Journal:  PLoS One       Date:  2015-02-11       Impact factor: 3.240

2.  The influence of different fever definitions on diagnostics and treatment after diagnosis of fever in chemotherapy-induced neutropenia in children with cancer.

Authors:  Stéphanie Wagner; Eva K Brack; Eveline Stutz-Grunder; Philipp Agyeman; Kurt Leibundgut; Oliver Teuffel; Roland A Ammann
Journal:  PLoS One       Date:  2018-02-20       Impact factor: 3.240

3.  Temperatures and blood counts in pediatric patients treated with chemotherapy for cancer, NCT01683370.

Authors:  Luana Lavieri; Christa Koenig; Oliver Teuffel; Philipp Agyeman; Roland A Ammann
Journal:  Sci Data       Date:  2019-07-03       Impact factor: 6.444

  3 in total

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