Literature DB >> 23261746

Evaluation of anti-inflammatory activity of selected legumes from Pakistan: in vitro inhibition of cyclooxygenase-2.

Muhammad Zia-Ul-Haq1, Premysl Landa, Zsófia Kutil, Mughal Qayum, Shakeel Ahmad.   

Abstract

Crude methanolic extracts of selected legumes namely, black gram (Vigna mungo L.), green gram (Vigna radiata (L.) R. Wilczek ), soybean (Glycine max (L.) Merr.) and lentil (Lens culinaris Medik.) were investigated for anti-inflammatory effects, using COX-2 producing PGE(2) inhibitory assay. Percentage inhibition observed was 73.93, 79.84, 92.17 and 74.47 for black gram, green gram, soybean and lentil respectively at 20μg/ml extract concentration. The 100μg/ml concentration showed increase in the percent inhibition except for soybean. This is the first report on COX-2 inhibitory potential of food legumes.

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Year:  2013        PMID： 23261746

Source DB:  PubMed          Journal:  Pak J Pharm Sci        ISSN： 1011-601X            Impact factor:   0.684


  4 in total

1.  Compositional studies and biological activities of some mash bean (Vigna mungo (L.) Hepper) cultivars commonly consumed in Pakistan.

Authors:  Muhammad Zia-Ul-Haq; Shakeel Ahmad; Shazia Anwer Bukhari; Ryszard Amarowicz; Sezai Ercisli; Hawa Z E Jaafar
Journal:  Biol Res       Date:  2014-05-30       Impact factor: 5.612

2.  Scientific basis for use of Pyrus pashia Buch.-Ham. ex D. Don. fruit in gastrointestinal, respiratory and cardiovascular ailments.

Authors:  Khalid Hussain Janbaz; Muhammad Zaeem Ahsan; Fatima Saqib; Imran Imran; Muhammad Zia-Ul-Haq; Muhammad Abid Rashid; Hawa Z E Jaafar; Marius Moga
Journal:  PLoS One       Date:  2015-03-18       Impact factor: 3.240

Review 3.  Polyphenol-Rich Lentils and Their Health Promoting Effects.

Authors:  Kumar Ganesan; Baojun Xu
Journal:  Int J Mol Sci       Date:  2017-11-10       Impact factor: 5.923

4.  Spectral, Anti-Inflammatory, Anti-Pyretic, Leishmanicidal, and Molecular Docking Studies, Against Selected Protein Targets, of a New Bisbenzylisoquinoline Alkaloid.

Authors:  Muhammad Alamzeb; William N Setzer; Saqib Ali; Behramand Khan; Mamoon-Ur- Rashid; Syed Muhammad Salman; Muhammad Omer; Javed Ali; Asad Ullah
Journal:  Front Chem       Date:  2021-12-17       Impact factor: 5.221
  4 in total

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