| Literature DB >> 23257527 |
Takuya Miki1, Tetsu Akimoto, Taro Sugase, Akihiko Numata, Naoko Otani, Yoshitaka Iwazu, Eri Takeshima, Yoshiyuki Morishita, Shigeaki Muto, Eiji Kusano.
Abstract
Rapidly progressive glomerulonephritis (RPGN) is characterized by the rapid deterioration of the renal function associated with crescent formation on renal biopsies. This report describes a case of RPGN caused by anti-glomerular basement membrane (GBM) glomerulonephritis in an elderly man with severe thrombocytopenia and a platelet count of 1.4 × 10(4)/µL. Thrombotic microangiopathy (TMA) and heparin-induced thrombocytopenia (HIT) were implicated in the severe decrease in platelets. This report also discusses the pathological background and clinical management of TMA and HIT among patients with anti-GBM glomerulonephritis.Entities:
Mesh：
Year: 2012 PMID： 23257527 DOI： 10.2169/internalmedicine.51.8507
Source DB: PubMed Journal: Intern Med ISSN： 0918-2918 Impact factor: 1.271