Literature DB >> 23257268

Photoactivated platelet-rich plasma therapy for a traumatic knee chondral lesion.

Julien Freitag1, Adele Barnard, Andrew Rotstein.   

Abstract

To evaluate the effect of combining photoactivation therapy with platelet-rich plasma injections in the treatment of a traumatic chondral lesion of the knee. A 38-year-old man presented with left-knee pain and swelling following a basketball injury. MRI demonstrated a full-thickness lateral tibial plateau chondral flap with subchondral cyst formation and marrow oedema. The patient underwent a course of photoactivated platelet-rich plasma (PAPRP) injections. Patient outcome measures included the numerical pain rating scale and the Western Ontario and McMaster Universities Arthritis Index 3.0 (WOMAC). Following treatment, the patient reported improvement in both pain and function as measured by the numerical pain-rating scale and WOMAC. MRI showed resolution of subchondral bone marrow bruising/oedema. No complications were noted. In this case report, PAPRP injections demonstrated improvement in all recorded outcome measures. Recognising the limitations of a single case report, the results highlight the need for more formal controlled trials to determine the potential use of PAPRP in the treatment of chondral lesions.

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Year:  2012        PMID: 23257268      PMCID: PMC4543717          DOI: 10.1136/bcr-2012-006858

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  21 in total

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Authors:  M B Schmidt; E H Chen; S E Lynch
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Review 3.  Chondral injuries.

Authors:  Robert A Sellards; Shane J Nho; Brian J Cole
Journal:  Curr Opin Rheumatol       Date:  2002-03       Impact factor: 5.006

4.  One-step osteochondral repair with cartilage fragments in a composite scaffold.

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Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2012-02-21       Impact factor: 4.342

5.  Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee.

Authors:  N Bellamy; W W Buchanan; C H Goldsmith; J Campbell; L W Stitt
Journal:  J Rheumatol       Date:  1988-12       Impact factor: 4.666

6.  Natural history of knee cartilage defects and factors affecting change.

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Review 7.  Natural history of bone bruises after acute knee injury: clinical outcome and histopathological findings.

Authors:  Atsuo Nakamae; Lars Engebretsen; Roald Bahr; Tron Krosshaug; Mitsuo Ochi
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2006-06-20       Impact factor: 4.342

8.  Pro- and anti-inflammatory cytokine content in human peripheral blood after its transcutaneous (in vivo) and direct (in vitro) irradiation with polychromatic visible and infrared light.

Authors:  Natalya A Zhevago; Kira A Samoilova
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9.  Outcome of untreated traumatic articular cartilage defects of the knee: a natural history study.

Authors:  K Donald Shelbourne; Sanjiv Jari; Tinker Gray
Journal:  J Bone Joint Surg Am       Date:  2003       Impact factor: 5.284

10.  Knee Injury and Osteoarthritis Outcome Score (KOOS)--development of a self-administered outcome measure.

Authors:  E M Roos; H P Roos; L S Lohmander; C Ekdahl; B D Beynnon
Journal:  J Orthop Sports Phys Ther       Date:  1998-08       Impact factor: 4.751

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  2 in total

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Authors:  Antonio Marmotti; Roberto Rossi; Filippo Castoldi; Eliana Roveda; Gianni Michielon; Giuseppe M Peretti
Journal:  Biomed Res Int       Date:  2015-05-05       Impact factor: 3.411

2.  Intra-articular injection of photo-activated platelet-rich plasma in patients with knee osteoarthritis: a double-blind, randomized controlled pilot study.

Authors:  Kade L Paterson; Melissa Nicholls; Kim L Bennell; Dan Bates
Journal:  BMC Musculoskelet Disord       Date:  2016-02-09       Impact factor: 2.362

  2 in total

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