Literature DB >> 23257191

Aging: one thing leads to another.

Marion Schmidt1, Brian K Kennedy.   

Abstract

Mitochondria deteriorate during the aging process, but the underlying mechanisms for the decline of this critical organelle are unknown. A new study indicates that in yeast an age-dependent reduction in vacuolar acidification leads to mitochondrial dysfunction through a surprising mechanism: loss of vacuolar neutral amino acid transport.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID： 23257191     DOI： 10.1016/j.cub.2012.11.016

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  4 in total

Review 1.  Dietary restriction, mitochondrial function and aging: from yeast to humans.

Authors:  Andrea Ruetenik; Antoni Barrientos
Journal:  Biochim Biophys Acta       Date:  2015-05-12

Review 2.  Role of asymmetric cell division in lifespan control in Saccharomyces cerevisiae.

Authors:  Ryo Higuchi-Sanabria; Wolfgang M A Pernice; Jason D Vevea; Dana M Alessi Wolken; Istvan R Boldogh; Liza A Pon
Journal:  FEMS Yeast Res       Date:  2014-10-13       Impact factor: 2.796

3.  Specific changes in mitochondrial lipidome alter mitochondrial proteome and increase the geroprotective efficiency of lithocholic acid in chronologically aging yeast.

Authors:  Anna Leonov; Anthony Arlia-Ciommo; Simon D Bourque; Olivia Koupaki; Pavlo Kyryakov; Paméla Dakik; Mélissa McAuley; Younes Medkour; Karamat Mohammad; Tamara Di Maulo; Vladimir I Titorenko
Journal:  Oncotarget       Date:  2017-05-09

Review 4.  Quasi-programmed aging of budding yeast: a trade-off between programmed processes of cell proliferation, differentiation, stress response, survival and death defines yeast lifespan.

Authors:  Anthony Arlia-Ciommo; Amanda Piano; Anna Leonov; Veronika Svistkova; Vladimir I Titorenko
Journal:  Cell Cycle       Date:  2014       Impact factor: 4.534
  4 in total

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