OBJECTIVE: The tumefactive variant of cerebral amyloid angiopathy (CAA) is rare. In this article we describe imaging findings associated with this entity and evaluate the role of susceptibility MRI sequences in its diagnosis. CONCLUSION: Our findings suggest that in elderly patients, susceptibility sequences should be part of prebiopsy MRI for tumefactive lesions. Identification of characteristic diffuse microhemorrhages should prompt inclusion of CAA in the differential diagnosis, targeted biopsy of the cortex and leptomeninges, and pathologic staining for CAA.
OBJECTIVE: The tumefactive variant of cerebral amyloid angiopathy (CAA) is rare. In this article we describe imaging findings associated with this entity and evaluate the role of susceptibility MRI sequences in its diagnosis. CONCLUSION: Our findings suggest that in elderly patients, susceptibility sequences should be part of prebiopsy MRI for tumefactive lesions. Identification of characteristic diffuse microhemorrhages should prompt inclusion of CAA in the differential diagnosis, targeted biopsy of the cortex and leptomeninges, and pathologic staining for CAA.
Authors: Michelle M Miller-Thomas; Adam L Sipe; Tammie L S Benzinger; Jonathan McConathy; Sarah Connolly; Katherine E Schwetye Journal: Radiographics Date: 2016 Jul-Aug Impact factor: 5.333
Authors: Claudia Uribe Roca; Fabio Maximiliano Gonzalez; Marta Ines Bala; Miguel Saucedo; Lucrecia Bandeo; Luciana Leon Cejas; Sol Pacha; Pablo Bonardo; Carlos Rugilo; Pablo Dezanzo; Rafael Torino; Gustavo Sevlever; Manuel Fernandez Pardal; Ricardo Reisin Journal: Psychiatry Investig Date: 2021-06-17 Impact factor: 2.505
Authors: Carlo Salvarani; Jonathan M Morris; Caterina Giannini; Robert D Brown; Teresa Christianson; Gene G Hunder Journal: Medicine (Baltimore) Date: 2016-05 Impact factor: 1.889