Literature DB >> 23254937

Structural biology: Membrane enzyme cuts a fine figure.

Michael S Wolfe.   

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Year:  2012        PMID： 23254937     DOI： 10.1038/nature11768

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  14 in total

1.  Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry.

Authors:  Zhuoru Wu; Nieng Yan; Liang Feng; Adam Oberstein; Hanchi Yan; Rosanna P Baker; Lichuan Gu; Philip D Jeffrey; Sinisa Urban; Yigong Shi
Journal:  Nat Struct Mol Biol       Date:  2006-11-10       Impact factor: 15.369

2.  Crystal structure of a rhomboid family intramembrane protease.

Authors:  Yongcheng Wang; Yingjiu Zhang; Ya Ha
Journal:  Nature       Date:  2006-10-11       Impact factor: 49.962

Review 3.  Presenilins and γ-secretase: structure, function, and role in Alzheimer Disease.

Authors:  Bart De Strooper; Takeshi Iwatsubo; Michael S Wolfe
Journal:  Cold Spring Harb Perspect Med       Date:  2012-01       Impact factor: 6.915

4.  Structure of a site-2 protease family intramembrane metalloprotease.

Authors:  Liang Feng; Hanchi Yan; Zhuoru Wu; Nieng Yan; Zhe Wang; Philip D Jeffrey; Yigong Shi
Journal:  Science       Date:  2007-12-07       Impact factor: 47.728

5.  Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity.

Authors:  M S Wolfe; W Xia; B L Ostaszewski; T S Diehl; W T Kimberly; D J Selkoe
Journal:  Nature       Date:  1999-04-08       Impact factor: 49.962

6.  A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.

Authors:  B De Strooper; W Annaert; P Cupers; P Saftig; K Craessaerts; J S Mumm; E H Schroeter; V Schrijvers; M S Wolfe; W J Ray; A Goate; R Kopan
Journal:  Nature       Date:  1999-04-08       Impact factor: 49.962

7.  Structure of a presenilin family intramembrane aspartate protease.

Authors:  Xiaochun Li; Shangyu Dang; Chuangye Yan; Xinqi Gong; Jiawei Wang; Yigong Shi
Journal:  Nature       Date:  2012-12-19       Impact factor: 49.962

8.  Identification of signal peptide peptidase, a presenilin-type aspartic protease.

Authors:  Andreas Weihofen; Kathleen Binns; Marius K Lemberg; Keith Ashman; Bruno Martoglio
Journal:  Science       Date:  2002-06-21       Impact factor: 47.728

Review 9.  Intramembrane proteolysis.

Authors:  Michael S Wolfe
Journal:  Chem Rev       Date:  2009-04       Impact factor: 60.622

10.  The mechanism of γ-Secretase dysfunction in familial Alzheimer disease.

Authors:  Lucía Chávez-Gutiérrez; Leen Bammens; Iryna Benilova; Annelies Vandersteen; Manasi Benurwar; Marianne Borgers; Sam Lismont; Lujia Zhou; Simon Van Cleynenbreugel; Hermann Esselmann; Jens Wiltfang; Lutgarde Serneels; Eric Karran; Harrie Gijsen; Joost Schymkowitz; Frederic Rousseau; Kerensa Broersen; Bart De Strooper
Journal:  EMBO J       Date:  2012-04-13       Impact factor: 11.598
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  2 in total

1.  Presenilin-like GxGD membrane proteases have dual roles as proteolytic enzymes and ion channels.

Authors:  Ivana Y Kuo; Jian Hu; Ya Ha; Barbara E Ehrlich
Journal:  J Biol Chem       Date:  2015-01-21       Impact factor: 5.157

2.  Presenilin adopts the ClC channel fold.

Authors:  Douglas L Theobald
Journal:  Protein Sci       Date:  2016-03-23       Impact factor: 6.725
  2 in total

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