| Literature DB >> 23253474 |
Luís Alberto de Sousa Rodrigues1, Ana Figueiras, Francisco Veiga, Rivelilson Mendes de Freitas, Lívio César Cunha Nunes, Edson Cavalcanti da Silva Filho, Cleide Maria da Silva Leite.
Abstract
Clays are materials commonly used in the pharmaceutical industry, either as ingredients or as active ingredients. It was observed that when they are administered concurrently, they may interact with drugs reducing their absorption. Therefore, such interactions can be used to achieve technological and biopharmaceutical advantages, regarding the control of release. This review summarizes bibliographic (articles) and technological (patents) information on the use of systems containing clays and clay minerals in modified drug delivery. In this area, formulations such natural clay, commercial clay, synthetic clay, composites clay-polymers, nanocomposites clay-polymers, films and hidrogels composites clay-polymers are used to slow/extend or vectorize the release of drugs and consequently they increase their bioavailability. Finally, this review summarizes the fields of technology and biopharmaceutical applications, where clays are applied.Entities:
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Year: 2012 PMID： 23253474 DOI： 10.1016/j.colsurfb.2012.10.068
Source DB: PubMed Journal: Colloids Surf B Biointerfaces ISSN： 0927-7765 Impact factor: 5.268