| Literature DB >> 23253320 |
Elisabeth Botelho-Nevers1, Cristina Socolovschi, Didier Raoult, Philippe Parola.
Abstract
Human rickettsioses caused by intracellular bacteria of the genus Rickettsia are distributed worldwide and are transmitted by arthropod vectors such as ticks, fleas, mites and lice. They have a wide range of manifestations from benign to life-threatening diseases. Mortality rates of up to 30% have been reported for some rickettsioses. Here, the authors will review in vitro and human studies of the various compounds that have been used for the treatment of Rickettsia spp. infections. The authors will also provide recommendations for the treatment of spotted fever and typhus group rickettsioses.Entities:
Mesh：
Substances：
Year: 2012 PMID： 23253320 DOI： 10.1586/eri.12.139
Source DB: PubMed Journal: Expert Rev Anti Infect Ther ISSN： 1478-7210 Impact factor: 5.091