Literature DB >> 23253126

Beyond the hundred dollar genome--drug discovery futures.

David L Selwood1.   

Abstract

The advent of silicon chip based technologies for genome sequencing promises continuing exponential falls in the reagent costs of sequencing. When every patient has a full genome sequence as part of their medical records the science of drug discovery and drug design must adapt and improve to meet this challenge. This series covers computational, and experimental approaches for small molecules and biologics. From the virtual patient - a computational model of a complete human being, through in silico screening to RNA editing and antibody directed therapies.
© 2012 John Wiley & Sons A/S.

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Year:  2013        PMID: 23253126     DOI: 10.1111/cbdd.12088

Source DB:  PubMed          Journal:  Chem Biol Drug Des        ISSN: 1747-0277            Impact factor:   2.817


  1 in total

1.  PANOPLY: Omics-Guided Drug Prioritization Method Tailored to an Individual Patient.

Authors:  Krishna R Kalari; Jason P Sinnwell; Kevin J Thompson; Xiaojia Tang; Erin E Carlson; Jia Yu; Peter T Vedell; James N Ingle; Richard M Weinshilboum; Judy C Boughey; Liewei Wang; Matthew P Goetz; Vera Suman
Journal:  JCO Clin Cancer Inform       Date:  2018-12
  1 in total

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